Edward Jenner, born in 1749 in Berkeley, Gloucestershire, England is widely recognized as the pioneer of the smallpox vaccine, a breakthrough that paved the way for the eventual eradication of the disease. This article traces Jenner's journey from his early education and apprenticeship under renowned surgeon John Hunter to his groundbreaking work on vaccination. Jenner's keen observations led him to hypothesize that cowpox could provide immunity against smallpox, which he confirmed through an experiment in 1796.
View Article and Find Full Text PDFIntroduction: The rise of antibiotic resistance poses a critical challenge to public health, particularly in managing infections caused by non-fermenting bacteria such as and This study aimed to determine the prevalent multi-drug resistance among non-fermentative Gram-negative bacteria isolated from hospitalized patients in a tertiary care center.
Material And Methods: A retrospective analysis was undertaken using one year of data from 2022 to 2023 to evaluate the antimicrobial resistance (AMR) profiles of and . The study assessed antibiotic resistance patterns, including piperacillin/tazobactam, carbapenems (imipenem, meropenem), ciprofloxacin, and colistin.
Background: Hepatitis B virus (HBV) infection poses significant occupational risks to healthcare workers (HCWs) worldwide. Understanding the knowledge, attitudes, and practices (KAPs) of HCWs regarding HBV infection and vaccination is crucial for developing effective preventive strategies. This study aims to assess the KAPs of the HCWs regarding HBV transmission, prevention, and vaccination in Saveetha Medical College and Hospital, Thandalam, Tamil Nadu.
View Article and Find Full Text PDFIntroduction: Healthcare-associated infections (HCAIs) and emerging multi-drug resistance in nosocomial pathogens are perceived as a serious public health threat. Hands of healthcare workers (HCWs) become routinely colonized during patient care, serving as vehicles for transmission and leading to HCAIs. Hand hygiene (HH) is a globally accepted tool to avoid the broadcast of dangerous microorganisms and prevent HCAIs.
View Article and Find Full Text PDFBackground -associated catheter-related bloodstream infections (CRBSIs) present a significant challenge in clinical settings, particularly among patients with central venous catheters (CVCs). Time-to-positivity (TTP) of blood cultures, an indicator of fungal load, may provide insights into infection prognosis and severity. This study evaluates the role of TTP in -associated bloodstream infections and its impact on patient outcomes.
View Article and Find Full Text PDFinfections commonly cause gastroenteritis and enteric fever but can also result in extraintestinal infections, especially in immunocompromised individuals. Although rare, infection in the head and neck region was found to be more common in diabetics and patients with malignancy. We present a unique case of a 52-year-old immunocompromised man with uncontrolled diabetes who developed a submandibular abscess due to Paratyphi B.
View Article and Find Full Text PDFAtypical infection usually presents with unusual symptoms in addition to gastroenteritis. Such atypical presentations can pose a challenge for diagnosis and treatment as they may be misdiagnosed, leading to delayed care and potential complications. Here we report an unusual case of spp.
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