Use of famotidine in adult patients with end-stage renal disease: assessment of dosing and mental status changes.

Background: Famotidine dosage adjustment is required in patients with chronic kidney disease. Since recommendations on the degree of famotidine dose reduction vary between references, a chart review was conducted to evaluate the tolerability of varying famotidine doses in adults with end-stage renal disease (ESRD).

Methods: An assessment was made of famotidine doses prescribed to patients with ESRD over a 7-year period in a university hospital.