One-Pot Synthesis of Carbon Nanodots in an Organic Medium with Aggregation-Induced Emission Enhancement (AIEE): A Rationale for "Enzyme-Free" Detection of Cholesterol.

Addressing the limitations associated with the detection of cholesterol, we present a one-pot synthesis of a carbon nanodot (CD) in an organic medium (CD) from a novel bile acid hydrazone-based organogel. Interestingly, CD possesses the aggregation-induced emission enhancement (AIEE) phenomenon, which rationally aids in the "enzyme-free" detection of cholesterol through a fluorescence turn-on mechanism. On dilution of the THF/water mixture of CD with its poor solvent (water), a 9.

Carbon-Dot-Coated Alginate Beads as a Smart Stimuli-Responsive Drug Delivery System.

In this work, we report a smart stimuli-responsive drug delivery system (DDS) that can release drug depending upon the amount of pathogen (MRSA) present in the target. A greater amount of MRSA in the system will lead to more release of drug and vice versa. Carbon-dot-coated novel alginate beads (CA-CD) exhibiting superior stability was successfully used as smart drug delivery vehicle.

Carbon dots rooted agarose hydrogel hybrid platform for optical detection and separation of heavy metal ions.

A robust solid sensing platform for an on-site operational and accurate detection of heavy metal is still a challenge. We introduce chitosan based carbon dots rooted agarose hydrogel film as a hybrid solid sensing platform for detection of heavy metal ions. The fabrication of the solid sensing platform is centered on simple electrostatic interaction between the NH3+ group present in the carbon dots and the OH- groups present in agarose.

β-Cyclodextrin and calix[4]arene-25,26,27,28-tetrol capped carbon dots for selective and sensitive detection of fluoride.

In this work we have designed a novel system based on carbon dots prepared from chitosan gel capped with β-cyclodextrin and calix[4]arene-25,26,27,28-tetrol for sensitive and selective detection of fluoride ions in aqueous media. Fluorescent carbon dots prepared from chitosan gel when capped with β-cyclodextrin and calix[4]arene-25,26,27,28-tetrol results in quenching of its fluorescence intensity. Introduction of F(-) ions to carbon dots capped with β-cyclodextrin and calix[4]arene-25,26,27,28-tetrol system results in enhancement and restoration of fluorescence intensity leading to detection of F(-) ion.

Green chitosan-carbon dots nanocomposite hydrogel film with superior properties.

In this work we report novel chitosan-carbon dots nanocomposite hydrogel films. A new green source "tea" was used as precursor for carbon dots (CDs). The electrostatic interaction of positive charge on chitosan and negative charge on CDs prepared from tea was used for the successful preparation of a stable and robust chitosan-carbon dots nanocomposite hydrogel film.

Novel carbon dot coated alginate beads with superior stability, swelling and pH responsive drug delivery.

Novel carbon dot coated alginate beads (CA-CD) exhibiting superior stability and swelling properties have been successfully prepared. CA-CD show exceptional stability in ambient condition and are stable at room atmosphere and temperature even after 60 days. Moreover, CA-CD show excessive swelling in comparison to calcium alginate (CA) beads.

In-situ and ex-situ chitosan-silver nanoparticle composite: comparison of storage/release and catalytic properties.

In this work storage of silver nanoparticles (Ag NPs) in chitosan gel and its subsequent release for catalytic reduction processes is investigated. The generation of small sized metal nanoparticles which acts as catalyst is prerequisite to progress of a catalytic reaction. We show that Ag NPs extracted from chitosan gel are less than 5 nm so very effective in catalysis.

Capped fluorescent carbon dots for detection of hemin: role of number of -OH groups of capping agent in fluorescence quenching.

We have successfully demonstrated the use of capped carbon dot systems, namely, CDs/ β -cd, CDs/LMH, and CDs/Suc, as fluorescent sensors for the detection of hemin. The capped carbon dot systems showed quenching of PL intensity in the presence of hemin. The minimum detection limit was determined to be ~1 μ M.