First serologic evidence of human hantavirus infection in Alagoas State in Northeastern Brazil.

Introduction: Hantavirus cardiopulmonary syndrome (HCPS) is rare in Northeastern Brazil.

Methods: Prospective surveillance was conducted over a two-year period in Alagoas State, Northeastern Brazil. The prevalence of anti-hantavirus N-antigen IgM and IgG in human serum samples was determined by enzyme-linked immunosorbent assay testing.