[Influence of thermolabile lethal toxin of Yersinia pseudotuberculosis on development of sea urchin embryos and biosynthesis of DNA and RNA in embryonic cells].

Influence of thermolabile lethal toxin of Y. pseudotuberculosis on the development of embryos of sea urchin (Strongylocentrotus intermedius) and on biosynthesis of nucleic acids in embryonic cells was studied. Thermolabile lethal toxin affected metabolic processes of cells by inhibiting DNA and RNA synthesis.

[Biological properties of heat-labile lethal toxin of Yersinia pseudotuberculosis].

The aim of the study was to assess the biological properties of heat-labile lethal protein toxin of Y. pseudotuberculosis. Toxin was extracted from Y.

[The action of Yersinia pseudotuberculosis heat stable lethal toxin on the biosynthesis of protein in vitro].

The results of the in vitro action of Y. pseudotuberculosis heat stable lethal toxin on the biosynthesis of protein are presented. The toxin was shown to inhibit the inclusion of exogenous amino acid into newly synthesized peptides.

[Effect of the thermostable toxin of Yersinia pseudotuberculosis on the oxidant and antioxidant activity of human blood leukocytes].

Y.pseudotuberculosis thermostable lethal toxin as shown to affect the functional activity of human blood leukocytes. Still neutrophils and monocytes exhibited different reaction to the introduction of the toxin.

[Thermostable Yersinia pseudotuberculosis toxin: its isolation, purification and the characteristics of its properties].

Heat-stable toxin, lethal for mice when administered parenterally (LD50 was equal to 4.5 micrograms/mouse), was isolated from Y. pseudotuberculosis grown at a temperature of 8-10 degrees C.

[Use of serum to thermostable toxin for identification of Yersinia pseudotuberculosis].

Serum to thermostable Y. pseudotuberculosis toxin is shown to induce agglutination of bacteria belonging to all 8 serologic variants of this species. No cross reactions with other enterobacterial species, including four Yersinia species, were detected.

[The temperature-induced early and late development of resistance to the bactericidal action of blood serum in Yersinia pseudotuberculosis].

Y. pseudotuberculosis strains were grown at 6 degrees-8 degrees C and then incubated at 37 degrees C. 3-6 hours later serum resistance appeared in the strains having plasmid virulence and producing outer membrane polypeptide with a molecular weight of 120 kD, known as P1.