Publications by authors named "Neda Daeifarshbaf"
Background: Hormonal imbalance is one of the important etiological factors for Oligoasthenoteratospermias (OAT).
Objective: This study aimed to evaluate the effects of hormonal changes including prolactin, TSH, testosterone, luteinizing hormone, follicle-stimulating hormone, and anti-Mullerian hormone on sperm DNA fragmentation in normal men compared with OAT to design a clinical algorithm for the comprehensive study of male factor infertilities.
Materials And Methods: We consecutively selected 60 candidates referred to the infertility clinic to collect the semen and blood samples.
Article Synopsis
- The study aims to identify a biomarker that can help select competent oocytes with good fertilization potential, focusing on the role of calcium ion fluctuations in oocyte maturation and activation.
- Bioinformatics analysis of calcium/calmodulin-binding genes (CBGs) was conducted, specifically examining the catalytic subunit of calcineurin (CaN), which is crucial in mediating calcium ion functions during human oogenesis.
- Results showed that elevated levels of the PPP3CB isoform in cumulus cells of mature oocytes indicate a reliable marker for their fertilization potential, emphasizing the need for further research to validate CaN Aβ as a biomarker for assisted reproduction techniques.
Background: Nowadays, the number of cancer survivors is significantly increasing as a result of efficient chemo/radio therapeutic treatments. Female cancer survivors may suffer from decreased fertility. In this regard, different fertility preservation techniques were developed.
View Article and Find Full Text PDFOdorant or olfactory receptors are mainly localized in the olfactory epithelium for the perception of different odors. Interestingly, many ectopic olfactory receptors with low expression levels have recently been found in nonolfactory tissues to involve in local functions. Therefore, we investigated the probable role of the olfactory signaling pathway in the surrounding microenvironment of oocyte.
View Article and Find Full Text PDFThe combination of bioceramics and stem cells has attracted the interest of research community for bone tissue engineering applications. In the present study, a combination of Bio-Oss(®) and type 1 collagen gel as scaffold were loaded with human adipose-tissue derived mesenchymal stem cells (AT-MSCs) after isolation and characterization, and the capacity of them for bone regeneration was investigated in rat critical size defects using digital mammography, multi-slice spiral computed tomography imaging and histological analysis. 8 weeks after implantation, no mortality or sign of inflammation was observed in the site of defect.
View Article and Find Full Text PDF