[Treatment of patients with abscess of prostate gland by the method of percutaneous punction].

Objectives: Demonstrate the treatment of prostatic abscess with a minimally invasive method - abscess puncture with aspiration of purulent fluid and injection of an antibiotic into abscess cavity.

Materials And Methods: Diagnosis of prostatic abscess of 23 patients using ultrasonography, computed tomography and magnetic resonance imaging of the pelvic region. 19 patients with the abscess within the prostatic capsule were treated with perineal percutaneous puncture method with aspiration of the abscess fluid and injection of antibiotics into cavity.

[Uroflowmetry in examination of the female with stress urinary incontinence].

Aim: Show the ability of uroflowmetry to record episodes of involuntary loss of urine at an altitude cough bursts.

Material And Methods: A total of 49 women with a genital prolapse and stress urinary incontinence. The study was conducted during bladder filling 150-300 ml of urine.

[The participation of matrix metalloproteinases-9 and TIMP-1 in formation of atrial fibrillation paroxisms in patients with metabolic syndrome].

The aim of this study was to estimate the role of matrix metalloproteinases activity (MMP-9, TIMP-1) and gene polymorphism at the patients with metabolic syndrome in combination with paroxysmal form of atrial fibrillation. The 60 patients with metabolic syndrome in combination with paroxysmal form of atrial fibrillation were investigated with estimation of serum levels of MMP-9, TIMP-1 and mutation of genes of angiotenzinogen 1 Thr 174 Met, angiotenzinogen 2 Met 235 Thr and apolipoprorein C3 C3238 G. In patients with metabolic syndrome in combination with paroxysmal form of atrial fibrillation the significant increase synthesis of MMP-9 level can lead to increase of atrial fibrillation paroxysms because of increase synthesis of collagen tissue in myocard and vessel walls.

[Erosions of the vaginal, bladder and urethral mucosa after transvaginal correction of genital prolapse and stress urinary incontinence using synthetic materials].

The article presents the results of treatment of 13 women with erosion of the vaginal mucosa with an exposure of the part of prosthesis and 4 women with the migration of fragments of the prosthesis into the lumen of the bladder or urethra after surgical correction of genital prolapse and stress urinary incontinence with the use of synthetic materials (Prolift, TVT operations). Interventions included the removal of part or all prosthesis from zone of erosion of the vaginal mucosa and removal of prosthesis migrated into the lumen of the bladder or urethra. Good results of operations were achieved in all cases.

[Dynamic magnetic resonance imaging of the pelvis in the differential diagnosis of types of urinary incontinence in women].

The technique was developed, and the results of static and dynamic magnetic resonance imaging of the pelvis in 52 women with clinically diagnosed descent or prolapse of internal genital organs are presented. Episodes ofinvoluntary urination during physical exertion were recorded in 42 women. The developed MRI method allows to fix not only the degree of prolapse of pelvic organs with an increase in intra-abdominal pressure (Valsalva maneuver, cough), but an involuntary opening of the urethra and its filling by contents of the bladder at the height of increased intra-abdominal pressure and the immediate closure of the urethra at the decrease of intra-abdominal pressure--leading features of stress urinary incontinence.

[Condition of the urinary tract and the kidneys in females with prolapse and descent of the internal genitalia].

Excretory urography (EU), retrograde cystography (RC), static and dynamic pelvic MRT, renoradiography (RRG) were performed in 82 females with descent and prolapse of the internal genitalia. The above examination identified four degrees of the urinary bladder descent. The latter descent of the third and fourth degree caused ureteral obstruction in 48.

[Synthetic prosthesis in surgical treatment of females with stress urinary incontinence combined with genital prolapse].

Simultaneous surgical treatment of females with genital prolapse and stress urinary incontinence using Gynecare Prolift, TVT techniques with use of mesh, colpo-urethrosuspension with threads corrected static disorders of the genital organs in 96.7 +/- 3.3% cases, resulted in adequate continence in 93.

[Surgical treatment of urinary stress incontinence in women by J. Lorenz method--an alternative to TVT operation].

The article presents a modified technique of J. Lorenz operation for urinary stress incontinence in females with suspension of the urethra with threads (three threads are used instead of the band as in TVT operation). J.

[Simultaneous operations for combined surgical diseases in urological practice].

The study covered 653 patients with a combination of two surgical urological diseases or one urinary disease with one abdominal disease. Simultaneous operations were made in 409 patients, staged surgical treatment was performed in 154 patients who rejected one stage treatment. Simultaneous surgery was contraindicated because of severe associated diseases in 90 patients.

Role of individual structural features of rabbit kidneys in the predisposition to gentamicin nephrotoxicity.

A relationship between congenital features in the structure of rabbit kidneys and sensitivity to gentamicin nephrotoxicity was revealed. Gentamicin nephrotoxicity is more pronounced in rabbits with lower diameter of nephron convoluted tubules and with smaller cells lining their lumen.

New biochemical mechanisms of the anticancer effect of Ukrain in the treatment of cancer of the urinary bladder.

The aim of this study was to elucidate the mechanisms of the anticancer effect of Ukrain by comparing the processes of formation of the pool of free amino acids and their derivatives in the blood plasma and tumor biopsy specimens and unchanged bladder tissue in 28 patients with T1N0M0 bladder cancer. The examination was carried out before and after Ukrain treatment (10 mg i.v.

Results of Ukrain monotherapy of prostate cancer.

This study included 15 patients with newly diagnosed prostate cancer with an average age of 71 years (62-85 years). The patients received Ukrain at a total dose of 100 mg (10 mg intravenously every second day, 10 injections altogether). After two to three injections of Ukrain, all the patients noted considerable subjective improvements in their state.

Ukrain therapy of stage T1N0M0 bladder cancer patients.

The aim of the present study was to evaluate the efficacy of Ukrain as a new treatment modality in 28 patients with stage T1N0M0 bladder cancer. The tumor dimensions varied from 0.5 x 0.

[Diagnosis and treatment of locally advanced cancer of the urinary bladder].

The term "locally advanced cancer of the urinary bladder" is discussed. The data on examination and treatment of 375 patients are presented to work out criteria of diagnosis of the disease. Such patients have been shown to reveal extensive lesions from bladder tumor coupled with such homeostatic disorders as hypoamino-acidemia, endotoxicosis, metabolic acidosis, immunity deficiency and disturbed hemoglobin-mediated transport of oxygen.

[Results of organ preserving treatment of T1,2 kidney tumors].

The results of organ-saving surgery performed for kidney tumor T1.2N0M0 in 21 patients are presented. The renal pole or a tumor-bearing sector of the parenchyma of the kidney was resected in all cases.

[Comparative evaluation of effectiveness of some methods of treatment in locally invasive cancer of the urinary bladder].

Five-year survival cumulative results have been used to assess the efficacy of treatment for locally extended carcinoma of the urinary bladder using different methods: radiation + resection of bladder + chemotherapy; radiation + cystectomy with ureterosigmoanastomosis+chemotherapy; radiation + cystectomy with ureterocutaneostomy + chemotherapy; chemoradiation treatment. In the group of patients with tumors T2(m)NoxMo, the best cumulative results for survival (65 and 70%) were obtained in cases of organ-saving surgery. In tumor T3a, bNox(+, -)Mo group, the best results for survival (31.

[The fate of bladder cancer patients who refused radical treatment].

Survival of 117 operable male patients who had refused treatment was compared to that of 267 male patients who had undergone radical therapy. It was shown that treatment did not influence five-year survival of patients with T cancer. The same tendency was observed for T4 tumors.

[The dispensary care and work disability expertise of bladder cancer patients following cystectomy].

A question of the principles and methods of medical prophylactic survey in patients with bladder cancer who have undergone cystectomy with subsequent ureterosigmoid anastomosis and ureterocutaneostomy is not currently developed. On a basis of 79 follow-ups of patients with bladder cancer after cystectomy, a procedure of prophylactic survey in the setting of regional oncologic dispensary and district polyclinic was worked out. It is stressed that it is necessary to follow up the patients for a possible relapse and metastasis development as well as complications of the upper urinary tract and kidneys and metabolic shifts (acidosis, dyselectrolytemia).

[The free amino acid content of the blood serum in bladder cancer patients].

The content of 18 amino acids in the blood serum was studied in 57 patients with T2-4 carcinoma of the bladder according to the stage of the process and the functional condition of the kidneys. Dysaminoacidemia was found in patients with T2 bladder carcinoma, which did not need correction; marked hypoaminoacidemia was encountered in stage T3-4 tumors. Chronic renal insufficiency (intermittent and terminal stages) is conductive to significant decrease of the blood amino acid level.

[Changes in protein metabolism and the free amino acid profile in bladder cancer].

Protein metabolism status was assessed by standard procedures versus tumor stage and nitrogen-excreting function of the kidneys in 250 cases of urinary bladder cancer. In addition, 18 amino acids in the blood were assayed in 63 patients. Standard methods of examination identified protein metabolism disturbances in patients with stage III-IV renal failure whereas amino acid profile showed changes at a much earlier stage.

[The epidemiology of rotavirus gastroenteritis].

The materials, comprehensively characterizing the water outbreaks of gastroenteritis with its etiology established and its clinico-epidemiological interpretation made, are presented. Along with other data, the water nature of the outbreak was verified by the detection of rotavirus antigen, made in the enzyme immunoassay, not only in patients, but also in water samples from the surface water source and from sewage. To isolate the infective agent from environmental objects, bentonite, a mineral sorbent, has been used for the first time.

[Causes of the functional disorder of the kidneys in patients with bladder cancer after cystectomy with ureterosigmoid anastomosis].

Cystectomy with ureterosigmoid anastomosis by modified Goodwin's technique was performed in 47 patients with local vesical cancer. Pre- and postoperative functional status of the kidneys was assessed by means of renography, excretory urography and laboratory tests. Unilateral or bilateral renal dysfunction developed within 12 to 18 months after surgery in 22.

[Use of natural sorbents for isolating enteroviruses and hepatitis A virus from water samples].

The data of the study on optimal conditions for the use of a mineral sorbent, bentonite, for isolation of hepatitis A virus and enteroviruses from water bodies are presented.