Time-related variations in viability of random pattern skin flaps: An experimental study in rats.

Chronobiological variations are in the fabric of life. The first ideas regarding the possible effects of circadian rhythm on surgical outcomes were published in the early 2000s. Some studies support and oppose this idea.

Outcomes of transcorneal electrical stimulation therapy in the early stages of retinitis pigmentosa.

Background: To investigate the effect of transcorneal electrical stimulation (TES) therapy in patients with retinitis pigmentosa (RP).

Methods: We performed TES therapy in 21 patients with RP in 12 sessions with 1-week intervals. The following parameters obtained before and after the TES therapy were compared statistically; the best corrected visual acuity (BCVA, logMAR), Ishihara color vision level, multifocal electroretinography (mf-ERG) response, automated visual field (VF) outcome, and the 25-item low vision quality-of-life (LVQOL) questionnaire points.

The effects of commonly used intravitreal steroids on proliferation index of ciliary body-derived mesenchymal stem cells: an in vitro study.

Aim: To investigate the effects of commonly used intravitreal steroids on survival and proliferation (namely, proliferation index) of ciliary body-derived mesenchymal stem cells (CB-MSC).

Methods: CB-MSCs were isolated from newborn rats' eye, and they were expanded in the medium. Commonly used intravitreal steroids such as dexamethasone (Dex) and triamcinolone acetonide (TA) were added into the medium at commonly used concentration in clinical practice (0.

Eye patching as a treatment for amblyopia in children aged 10-16 years.

Purpose: To investigate the effects of full-time patching regimen on the treatment of amblyopia in children aged 10-16 years.

Methods: Forty-seven patients with a mean age of 12.09 ± 1.

Concise review: induced pluripotent stem cells and lineage reprogramming: prospects for bone regeneration.

Bone tissue for transplantation therapies is in high demand in clinics. Osteodegenerative diseases, in particular, osteoporosis and osteoarthritis, represent serious public health issues affecting a respectable proportion of the elderly population. Furthermore, congenital indispositions from the spectrum of craniofacial malformations such as cleft palates and systemic disorders including osteogenesis imperfecta are further increasing the need for bone tissue.

Penetration of topically applied diclofenac and ketorolac into the aqueous humour and subretinal fluid: randomized clinical trial.

Objective: To determine the level of intraocular penetration of diclofenac sodium and ketorolac tromethamine into the aqueous humour and subretinal fluid.

Design: Prospective randomized clinical trial.

Participants: Twenty eyes scheduled for retinal detachment surgery and 17 eyes scheduled for cataract surgery.

Conventional surgery for complicated retinal detachment in silicone oil-filled eyes.

Purpose: To evaluate the anatomic and functional outcomes of conventional surgery in silicone oil (SO)-filled eyes with complicated retinal detachment (RD).

Methods: The records of patients who underwent scleral buckling surgery for complex RD in SO-filled eyes were retrospectively reviewed. Conventional RD surgery involved a 2.

Focal posterior pole viral retinitis.

Purpose: To describe the clinical features of an atypical form of viral retinitis in immunocompetent patients.

Methods: This was a retrospective noncomparative case series. The charts of 8 patients diagnosed with and treated for focal posterior viral retinitis were reviewed.

Takayasu's disease and secondary ocular ischemic syndrome.

Takayasu's, or "pulseless," disease is a rare, idiopathic, chronic granulomatous vasculitis that affects large arterial blood vessels. Ocular manifestations occur as a consequence of obliteration of the carotid artery, and ocular ischemia may develop. A 14-year-old girl with progressive visual loss and ocular ischemic syndrome secondary to Takayasu's disease is described.

Are cefuroxime and vancomycin really safe on the corneal endothelial cells?

Purpose: To investigate the biochemical changes of the oxidant/antioxidant balance in corneal tissue, and determine the relative corneal endothelial toxicities of the following intracameral antibiotic agents: cefuroxime and vancomycin.

Methods: The experiment was conducted using New Zealand rabbits. The rabbits were randomly divided into three experimental groups as follows: cefuroxime group (n=10), vancomycin group (n=10), and control group (n=10).

Oxidative stress of intracameral lidocaine and levobupivacaine on ocular tissues.

Background: To investigate the biochemical changes on the oxidant/antioxidant balance in corneal and lens tissues in rabbits, and to determine the relative corneal endothelial toxicities following the injection of intracameral anaesthetic agents: levobupivacaine 0.5% or lidocaine 2%.

Methods: The experiment was conducted using New Zealand rabbits.

Retinal nerve fiber layer thickness in chronic renal failure without diabetes mellitus.

Purpose: To evaluate the retinal nerve fiber layer (RNFL) thickness in patients with chronic renal failure (CRF) without diabetes mellitus by using optical coherence tomography (OCT).

Methods: Sixty-six eyes of 33 patients with CRF were evaluated. Eighteen patients have been treated with hemodialysis (group 1) and 15 patients have been treated with peritoneal dialysis (group 2).

Duration of renal failure as risk factor for conjunctival squamous metaplasia.

Objective: To assess ocular surface changes in patients with chronic renal failure (CRF), to compare the results with the duration of illness.

Study Design: Impression cytology from 48 patients with CRF on regular hemodialysis and 16 age- and sex-matched control subjects were studied. Specimens were taken from the temporal bulbar conjunctiva using cellulose acetate filter paper.

Bilateral leukocoria in infant with afibrinogenemia.

Purpose: To report a bilateral leukocoria case in a patient suffering from afibrinogenemia.

Methods: An observational case where congenital afibrinogenemia was presented with bilateral retinal and vitreous hemorrhages that proceeded to vitreoretinal surgery was presented. In addition, complete ophthalmic and radiological examinations and vitreoretinal surgery were performed.

Axenfeld-Rieger syndrome and pseudotruncus arteriosus.

Axenfeld-Rieger syndrome (ARS) is an autosomal dominant disorder. It is described as the association of malformation of the anterior chamber of the eye with extraocular anomalies. Cardiovascular defects are considered an occasional findings with this syndrome.

Decompression retinopathy after Ahmed glaucoma valve implantation in a patient with congenital aniridia and pseudophakia.

We present the case of a 16-year-old adolescent boy with congenital aniridia and pseudophakia who developed decompression retinopathy in a glaucomatous eye after Ahmed glaucoma valve implantation combined with anterior vitrectomy. On the first postoperative day, dot and blot-shaped hemorrhages scattered in the posterior pole were observed. The hemorrhages resolved over 6 months, and the visual acuity returned to the preoperative level.