Publications by authors named "Neama I Ali"
Genetic characterization and its association with quantitative traits in local breeds are important tools for the genetic improvement and sustainable management of animal genetic resources. Myogenic regulatory factor 5 (MYf5) and POU class 1 homeobox 1 (POU1F1) are candidate genes which play important roles in growth and development of mammals. The present study aims to detect the genetic diversity of the MYf5 and POU1F1 genes in four local Egyptian rabbit breeds and their association with growth traits, using PCR-restriction enzyme (PCR-RFLP), PCR-single-strand conformational polymorphism (PCR-SSCP), and direct sequencing techniques.
View Article and Find Full Text PDFArticle Synopsis
- - The study assessed the growth performance and gut microbiota differences in two rabbit breeds, Native Middle-Egypt (NMER) and Giant Flanders (GF), from 5 to 12 weeks of age, using 16S rRNA gene sequencing to analyze gut samples.
- - Results showed that GF rabbits had better growth metrics, such as weight gain and villus height in the jejunum, compared to NMER rabbits, with their gut microbiota exhibiting beneficial bacterial compositions.
- - Significant correlations were found between specific gut microbiota in the jejunum and cecum of different breeds and their weight gain, indicating that the healthy microbiota in GF may help mitigate pathogenic effects in these rabbits.
Camels are considered an important food source in North Africa. Trypanosomiasis in camels is a life-threatening disease that causes severe economic losses in milk and meat production. Therefore, the objective of this study was to determine the trypanosome genotypes in the North African region.
View Article and Find Full Text PDFBackground: Genetic variants of the GDF9 gene were considered to be the potent gene markers for improving fecundity traits in Egyptian sheep and goats. Also, these favorable gene variants could be applied in the breeding program by gene-assisted selection (GAS), aiming towards the potential amelioration of reproduction and production in such small ruminants. The present investigation was designed to evaluate the genetic variants of the GDF9 gene on fecundity traits including the mean number of lambing "MNL" and mean number of twin production "MNTP" of Egyptian sheep and goats.
View Article and Find Full Text PDFTowards breast cancer targeting: Synthesis of tetrahydroindolocarbazoles, antibreast cancer evaluation, uPA inhibition, molecular genetic and molecular modelling studies.
Bioorg Chem
December 2019
A series of some new tetrahydroindolocarbazole derivatives has been synthesized. The structure of the synthesized compounds has been confirmed by different spectroscopic techniques such as IR, NMR, elemental analysis and mass spectrometry. The target compounds were evaluated for their antitumor activity against breast cancer cell line MCF-7, their GI% and their LC have been determined.
View Article and Find Full Text PDFAim: Native rabbits in smallholder system are considered as important genetic resources, and the present study was aimed to study the genetic and phenotypic characterization and detection of the maternal origin of the native rabbit populations located at the Middle of Egypt.
Materials And Methods: A survey of native rabbit populations was conducted in three governorates (Fayum [FY], Beni Suef [BN], and El Menia [MN]). The phenotypic characterization of rabbits included the profile body of the head, ears, eyes, neck, and legs and the coat colors.