Publications by authors named "Neal T Collins"
Cancer Prev Res (Phila)
April 2009
Article Synopsis
- The Adenoma Prevention with Celecoxib Trial studied celecoxib, a Cox-2 inhibitor, for preventing colorectal adenomas in high-risk patients, comparing it to a placebo.
- Results indicated that celecoxib significantly reduced adenoma incidence but raised the risk of cardiovascular events compared to placebo.
- An extension of the study found similar rates of adverse events across groups, but higher risks of cardiovascular issues for those taking celecoxib, particularly for patients with a history of heart disease.
