Biochemical and histological insights of 1,4-polyisoprene isolated from Sphenocentrum jollyanum pierre (menispermaceae) stem in wound healing activity in streptozotocin-induced diabetic rats.

Ethnopharmacological Relevance: Sphenocentrum jollyanum whole stem extract is used traditionally in combination with its leaves to treat chronic wounds and also ameliorate conditions that exacerbate wounds such as diabetes mellitus.

Aim Of The Study: The study isolated the major wound healing bioactive compound from the non-polar fraction of S. jollyanum extract and evaluated the in vivo wound healing activity of a 0.