The interplay between microRNAs and Nrf2 signaling in human cancers.

MicroRNAs (miRNAs), as a class of nonprotein-coding RNAs, post-transcriptionally regulate the expression of target genes by base pairing to 3'-untranslated regions (3'-UTRs). Nuclear factor E2-related factor 2 (Nrf2) has been identified as a critical component of the antioxidant defense mechanism. Dysregulation is associated with chemoresistance and radioresistance in cancerous cells.

Effect of Magnetorheological Grease's Viscosity to the Torque Performance in Magnetorheological Brake.

Recently, magnetorheological grease (MRG) has been utilized in magnetorheological (MR) brakes to generate a braking torque based on the current applied. However, the high initial viscosity of MRG has increased the off-state torque that led to the viscous drag of the brake. Therefore, in this study, the off-state viscosity of MRG can be reduced by the introduction of dilution oil as an additive.

Field-Dependent Rheological Properties of Magnetorheological Elastomer with Fountain-Like Particle Chain Alignment.

Magnetorheological elastomer (MRE) consists of magnetic particles known as carbonyl iron (CIPs), which have been locked in a silicone-based matrix, in various alignments. However, current MRE exhibits inadequate rheological properties due to several issues such as particle alignments. Therefore, in this study, a new approach of the particle alignment of CIPs in MRE, namely fountain-like structure, is introduced.

Non-parametric multiple inputs prediction model for magnetic field dependent complex modulus of magnetorheological elastomer.

This study introduces a novel platform to predict complex modulus variables as a function of the applied magnetic field and other imperative variables using machine learning. The complex modulus prediction of magnetorheological (MR) elastomers is a challenging process, attributable to the material's highly nonlinear nature. This problem becomes apparent when considering various possible fabrication parameters.

The Effect of Graphite Additives on Magnetization, Resistivity and Electrical Conductivity of Magnetorheological Plastomer.

Common sensors in many applications are in the form of rigid devices that can react according to external stimuli. However, a magnetorheological plastomer (MRP) can offer a new type of sensing capability, as it is flexible in shape, soft, and responsive to an external magnetic field. In this study, graphite (Gr) particles are introduced into an MRP as an additive, to investigate the advantages of its electrical properties in MRPs, such as conductivity, which is absolutely required in a potential sensor.

Dual Properties of Polyvinyl Alcohol-Based Magnetorheological Plastomer with Different Ratio of DMSO/Water.

Polyvinyl alcohol (PVA)-based magnetorheological plastomer (MRP) possesses excellent magnetically dependent mechanical properties such as the magnetorheological effect (MR effect) when exposed to an external magnetic field. PVA-based MRP also shows a shear stiffening (ST) effect, which is very beneficial in fabricating pressure sensor. Thus, it can automatically respond to external stimuli such as shear force without the magnetic field.

Effect of Mould Orientation on the Field-Dependent Properties of MR Elastomers under Shear Deformation.

In this study, magnetorheological elastomer (MRE) was fabricated using an electromagnetic device with a new configuration mold at the orientation of 0°, 45° and 90°. This new curing concept enhanced the alignment of carbonyl iron particles (CIPs) within the silicone matrix in the presence of silicone oil (SO) during solidifying, by eliminating air gaps to prevent magnetic flux losses. Using a mold made of steel, which is a magnetic material, the mold functions as a guide for concentrated magnetic flux of 0.

Rheological Performance of Magnetorheological Grease with Embedded Graphite Additives.

The use of highly viscous grease as a medium in magnetorheological grease (MRG) provides the benefit of avoiding sedimentation from occurring. However, it limits the expansion of yield stress in the on-state condition, thus reducing the application performance during operation. Therefore, in this study, the improvement in the rheological properties of MRG was investigated through the introduction of graphite as an additive.

Loss Factor Behavior of Thermally Aged Magnetorheological Elastomers.

Polymer composites have been widely used as damping materials in various applications due to the ability of reducing the vibrations. However, the environmental and surrounding thermal exposure towards polymer composites have affected their mechanical properties and lifecycle. Therefore, this paper presents the effect of material-temperature dependence on the loss factor and phase shift angle characteristics.

An Insight into Amorphous Shear Band in Magnetorheological Solid by Atomic Force Microscope.

Micro mechanism consideration is critical for gaining a thorough understanding of amorphous shear band behavior in magnetorheological (MR) solids, particularly those with viscoelastic matrices. Heretofore, the characteristics of shear bands in terms of formation, physical evolution, and response to stress distribution at the localized region have gone largely unnoticed and unexplored. Notwithstanding these limitations, atomic force microscopy (AFM) has been used to explore the nature of shear band deformation in MR materials during stress relaxation.

The Effect of Microparticles on the Storage Modulus and Durability Behavior of Magnetorheological Elastomer.

This paper presents the effect of the micro-sized particles on the storage modulus and durability characteristics of magnetorheological elastomers (MREs). The initial phase of the investigation is to determine any associations among the microparticles' weight percent fraction (wt%), structure arrangement, and the storage modulus of MRE samples. In order to carry out this, both isotropic and anisotropic types of MRE samples consisting of the silicone rubber matrix and 50, 60, 70, 75, and 80 wt% microparticles of carbonyl iron fractions are prepared.

Catalytic oxidative desulfurisation over Co/Fe-γAlO catalyst: performance, characterisation and computational study.

The world faces the challenge to produce ultra-low sulfur diesel with low-cost technology. Therefore, this research emphasised on production of low sulfur fuel utilising nanoparticle catalyst under mild condition. A small amount of cobalt oxide (10-30 wt%) was introduced into the Fe/AlO catalyst through the wet impregnation method.

Microstructural behavior of magnetorheological elastomer undergoing durability evaluation by stress relaxation.

The widespread use of magnetorheological elastomer (MRE) materials in various applications has yet to be limited due to the fact that there are substantial deficiencies in current experimental and theoretical research on its microstructural durability behavior. In this study, MRE composed of silicon rubber (SR) and 70 wt% of micron-sized carbonyl iron particles (CIP) was prepared and subjected to stress relaxation evaluation by torsional shear load. The microstructure and particle distribution of the obtained MRE was evaluated by a field emission scanning electron microscopy (FESEM).

Sensitivities of Rheological Properties of Magnetoactive Foam for Soft Sensor Technology.

Magnetoactive (MA) foam, with its tunable mechanical properties and magnetostriction, has the potential to be used for the development of soft sensor technology. However, researchers have found that its mechanical properties and magnetostriction are morphologically dependent, thereby limiting its capabilities for dexterous manipulation. Thus, in this work, MA foam was developed with additional capabilities for controlling its magnetostriction, normal force, storage modulus, shear stress and torque by manipulating the concentration of carbonyl iron particles (CIPs) and the magnetic field with regard to morphological changes.

Magnetic and Tunable Sound Absorption Properties of an In-Situ Prepared Magnetorheological Foam.

Conventional polyurethane foam has non-tunable sound absorption properties. Here, a magneto-induced foam, called magnetorheological (MR) foam, was fabricated with the feature of being able to tune sound absorption properties, primarily from the middle- to higher-frequency ranges. Three different samples of MR foams were fabricated in situ by varying the concentration of Carbonyl Iron Particles (CIPs) (0, 35, and 75 wt.

Systematic Review on the Effects, Roles and Methods of Magnetic Particle Coatings in Magnetorheological Materials.

Magnetorheological (MR) material is a type of magneto-sensitive smart materials which consists of magnetizable particles dispersed in a carrier medium. Throughout the years, coating on the surface of the magnetic particles has been developed by researchers to enhance the performance of MR materials, which include the improvement of sedimentation stability, enhancement of the interaction between the particles and matrix mediums, and improving rheological properties as well as providing extra protection against oxidative environments. There are a few coating methods that have been employed to graft the coating layer on the surface of the magnetic particles, such as atomic transfer radical polymerization (ATRP), chemical oxidative polymerization, and dispersion polymerization.

The Rheological Studies on Poly(vinyl) Alcohol-Based Hydrogel Magnetorheological Plastomer.

The freezing-thawing method has been commonly used in the preparation of polyvinyl alcohol hydrogel magnetorheological plastomer (PVA HMRP). However, this method is complex and time consuming as it requires high energy consumption and precise temperature control. In this study, PVA HMRP was prepared using a chemically crosslinked method, where borax is used as crosslinking agent capable of changing the rheological properties of the material.

Solvent Dependence of the Rheological Properties in Hydrogel Magnetorheological Plastomer.

Chemically crosslinked hydrogel magnetorheological (MR) plastomer (MRP) embedded with carbonyl iron particles (CIPs) exhibits excellent magnetic performance (MR effect) in the presence of external stimuli especially magnetic field. However, oxidation and desiccation in hydrogel MRP due to a large amount of water content as a dispersing phase would limit its usage for long-term applications, especially in industrial engineering. In this study, different solvents such as dimethyl sulfoxide (DMSO) are also used to prepare polyvinyl alcohol (PVA) hydrogel MRP.

Hsp72 antigen expression in the proliferative compartment of involved psoriatic epidermis.

Oxidative damage to growth regulatory proteins has been implicated in the aetiology of psoriasis. However, the transient synthesis of heat shock proteins has been shown to protect cells against the adverse effects of oxidative and other forms of physiological stress. This study has used an hsp72 monoclonal antibody to measure inducible 72 kDa heat shock protein expression in heat stressed normal human skin and established plaque psoriasis.

Erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis in northeastern Malaysia.

Background: Previous studies have reported that drugs and infections are common causes of erythema multiforme (EM) and Stevens-Johnson syndrome (SJS). Toxic epidermal necrolysis (TEN) is mainly related to drugs. No study has been conducted in Kelantan, the northeastern state of Malaysia, to assess these cutaneous reactions.

Renal stones in Kelantan, Malaysia--has the pattern changed?

Records of 183 patients with renal stones managed at Hospital Universiti Sains Malaysia between 1985 and 1995 were retrospectively evaluated. The commonest symptom was lumbar pain which may be associated with either frequency, blood stained urine or dysuria. One hundred and sixty-one patients (88%) had upper tract stones while the remainder had lower tract stones.

The pattern of chronic renal failure in Kelantan, northeastern state of Malaysia.

The pattern and outcome of patients with chronic renal failure (CRF) in Kelantan, the northeastern state of Malaysia was determined. A total of 60 patients with CRF managed at the Hospital Universiti Sains Malaysia between January 1991 and June 1993 were reviewed retrospectively. The prevalence of CRF was 24.