Publications by authors named "Nazlihan Boyaci Dundar"
Article Synopsis
- This study investigates the link between sepsis-induced acute kidney injury (AKI) and worse outcomes in patients in the intensive care unit (ICU), focusing on identifying risk factors for new-onset AKI among septic patients who initially had no kidney issues.
- Conducted at Gazi University Hospital, the research involved analyzing data from septic patients aged 18 and older, looking at demographics and clinical factors to determine predictors of AKI development and mortality rates.
- Results showed a significant incidence of new-onset AKI (36%), particularly linked to factors like invasive mechanical ventilation, new-onset shock, and higher APACHE-II scores, all of which correlated with longer ICU stays and increased mortality risk.*
Objective: This study aimed to investigate the relationship between procalcitonin (PCT) kinetic and estimated glomerular filtration rates (eGFR) in critically ill patients who had Gram-negative primary bloodstream infection (GN-BSI) and responded to the antimicrobial therapy.
Materials And Methods: This single-centered study was retrospective and observational. Critically ill GN-BSI patients over 18 years old who had clinical and microbiological responses to antibiotic treatment were included in the study.
Article Synopsis
- Critically ill cirrhotic patients face a high mortality risk from acute-on-chronic liver failure, and while traditional scoring systems like MELD and Child-Pugh provide some insight, they have limitations that need addressing.* -
- A study involving 175 of these patients showed that the lactate/albumin ratio (LAR) could be a useful prognostic tool, comparable to established scores, with higher ratios linked to increased ICU mortality.* -
- The findings suggest that LAR, alongside the SOFA score assessed at 48 hours, could help predict outcomes and inform treatment strategies, paving the way for further research to validate these results.*
Purpose: A prompt and effective immune response is required for clearance of pathogens but exaggerated states of inflammation can cause extensive collateral damage to the host. We have previously used a rapid near-patient assay that measures the functional capacity of neutrophils to produce reactive oxygen species (ROS) to show that values are elevated in patients with severe COVID-19 or sepsis. Here, we assess the utility of longitudinal ROS measurements to monitor and predict mortality outcome for patients with COVID-19 infection being treated in an ICU setting.
View Article and Find Full Text PDFEvaluation of prevalance and risk factors for bloodstream infection in severe coronavirus disease 2019 (COVID-19) patients.
Antimicrob Steward Healthc Epidemiol
February 2022
Objectives: In this study, we sought to determine the prevalence of bloodstream infection (BSI) in severe coronavirus disease 2019 (COVID-19) patients and to determine the risk factors of BSI in critical COVID-19 patients.
Design: Retrospective, descriptive study between March 2020 and January 2021.
Setting: An 1,007-bed university hospital.
Ibrutinib-associated alveolar hemorrhage and spontaneous hemothorax.
Kardiochir Torakochirurgia Pol
March 2022
Background/aim: The aim of the study was to investigate whether treating haematological malignancy (HM) patients in a separate intensive care unit (ICU) would reduce ICU mortality.
Materials And Methods: HM patients treated by the same ICU team in a general medical ICU (GM-ICU) and a separate haematology ICU (H-ICU) were included in this study. Patients’ demographic characteristics and ICU data were recorded retrospectively.
Background/aim: Pneumonia is the most serious clinical presentation of COVID-19. This study aimed to determine the demographic, clinical, and laboratory findings that can properly predict COVID-19 pneumonia.
Materials And Methods: This study was conducted in the Gazi University hospital.