Early Oncological and Functional Outcomes of Prostate Capsule Sparing Cystectomy Compared with Standard Radical Cystectomy.

Introduction And Objectives: A comparative study of standard radical cystectomy and prostate capsule sparing radical cystectomy regarding functional and oncological outcomes.

Materials And Methods: A randomized study of 96 patients with transitional cell carcinoma of the bladder (December 2014 - June 2016) was done. We excluded cases with preoperative T4 staging, lymphadenopathy, prostatic specific antigen > 4 ng/dl, and cases with positive biopsies from the bladder neck, trigone, and/or prostatic urethra.

Potential of used frying oil in paving material: solution to environmental pollution problem.

The improper disposal of used frying oil (UFO) presents numerous ecological, environmental and municipal problems. Of great concern is the resultant blockage of municipal drainage systems and water treatment facilities, harm to wildlife when they become coated in it and detriment to aquatic life and ecosystems due to the depletion of the oxygen content in water bodies such as rivers and lakes that have become contaminated. Statistics show that in Trinidad and Tobago, in excess of one million liters of used cooking oil is collected annually from various restaurant chains.

Rutting and Fatigue Cracking Resistance of Waste Cooking Oil Modified Trinidad Asphaltic Materials.

The influence of waste cooking oil (WCO) on the performance characteristics of asphaltic materials indigenous to Trinidad, namely, Trinidad Lake Asphalt (TLA), Trinidad Petroleum Bitumen (TPB), and TLA : TPB (50 : 50) blend, was investigated to deduce the applicability of the WCO as a performance enhancer for the base asphalt. The rheological properties of complex modulus (G (∗) ) and phase angle (δ) were measured for modified base asphalt blends containing up to 10% WCO. The results of rheology studies demonstrated that the incremental addition of WCO to the three parent binders resulted in incremental decreases in the rutting resistance (decrease in G (∗) /sinδ values) and increases in the fatigue cracking resistance (decrease in G (∗) sinδ value).

Synthesis of antisense oligonucleotides conjugated to a multivalent carbohydrate cluster for cellular targeting.

Carrier-mediated delivery holds great promise for significantly improving the cellular uptake and therefore the therapeutic efficacy of antisense oligonucleotides in vivo. A multivalent carbohydrate recognition motif for the asialoglycoprotein receptor has been designed for tissue- and cell-specific delivery of antisense drugs to parenchymal liver cells. To combine low molecular weight with high receptor affinity, the synthetic ligand contains three galactosyl residues attached to a cholane scaffold via epsilon-aminocapramide linkers.