Relationship of RIC-3 gene rs1528133 polymorphism with varying degrees of body weight and eating behavior.

Aims: The aim of this study was to determine the allele frequencies of resistance to inhibitors of cholinesterase 3 homologue (RIC-3) gene rs1528133 polymorphism in overweight+obese+morbid obese and non-obese (non-OB) subjects. The effects of rs1528133 genotypes on anthropometric, diabetes and obesity related parameters, self-reported macronutrient intake and drugs were also evaluated. The study was performed on overweight+obese+morbid obese and non-obese subjects.

Relationship of transcription factor 7 like 2 gene rs7903146 variation with type 2 diabetes and obesity related parameters.

Aims: The allele frequencies of transcription factor 7 like 2 (TCF7L2) gene rs7903146 polymorphism in type 2 diabetes mellitus (T2DM) and non-T2DM controls were determined.

Methods: TCF7L2 rs7903146 genotypes were determined with qPCR.

Results: The TCF7L2 gene rs7903146 genotype frequencies for homozygous wild type (C/C), heterozygous (C/T) and homozygous polymorphic (T/T) for T2DM patients were determined, respectively, as 71.

High prevalence of obesity and diabetes mellitus in Konya, a central Anatolian city in Turkey.

Introduction: The objective of this study was to determine the prevalence of overweight, obesity, impaired fasting glucose, diabetes and the relationship between adiposity and carbohydrate metabolism, by age and gender in Konya, a city in central Anatolia.

Methods: A cross-sectional population based survey was performed. One month before the field survey a media campaign was started in each district by local municipalities.