Publications by authors named "Nazia Fairooz Alam"
Methylenetetrahydrofolate reductase (MTHFR) plays a crucial role in regulating one-carbon metabolism. Polymorphisms within the MTHFR gene have been found to increase the risk of breast cancer in different populations. In this study, we evaluated the association of polymorphisms of the MTHFR gene (rs1801133 and rs1801131) with the risk of breast cancer in the Bangladeshi population.
View Article and Find Full Text PDFArticle Synopsis
- Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer primarily linked to Merkel cell polyomavirus (MCPyV), which promotes tumor growth through its large T (LT) antigens.
- The study aims to identify small natural antiviral compounds that can inhibit the proliferation of MCC by targeting the LT protein, using advanced computational drug design techniques.
- From screening 2,190 phytochemicals, five promising compounds were identified with high binding energy values, highlighting their potential as therapeutic agents against MCPyV-related cancers.