Publications by authors named "Nazia Begum"
Background and objective The term cognitive flexibility refers to the ability of the students to adapt to a challenging environment. This quality has been found to enhance creativity and skills for innovation among medical students who are expected to face a taxing environment in clinical settings. Medical students should be competent enough to address the problems on their own and work with autonomy.
View Article and Find Full Text PDFPurpose: To identify the factors affecting the quality of life (QoL) in adults with keratoconus, using the disease-specific Keratoconus Outcomes Research Questionnaire (KORQ).
Methods: In this cross-sectional study, 574 patients with keratoconus completed the 29-item KORQ (18-item activity limitations and 11-item symptoms subscales) and demographic information. Based on mean corneal curvature to grade keratoconus severity, participants were categorised into four groups: mild <48 dioptres [D]; moderate: 48 to 53 D; advanced: 54 to 55 D and severe: >55D.
Role of high-fat diet on letrozole-induced polycystic ovarian syndrome in rats.
Eur J Pharmacol
February 2022
Article Synopsis
- Polycystic ovary syndrome (PCOS) is a common hormonal disorder affecting women of reproductive age, and the study aimed to create a better animal model for PCOS by combining letrozole (LET) treatment with a high-fat diet (HFD).
- The results showed that both the LET and LET + HFD groups developed ovarian cysts and had hormonal imbalances, with higher testosterone but lower estradiol and progesterone levels.
- The LET + HFD group exhibited significant metabolic changes, such as increased body weight and altered blood markers, suggesting it is a more accurate representation of the metabolic issues seen in human PCOS compared to the LET-only model, which lacked these metabolic anomalies.
Metastasis is one of the predisposing factors for cancer-related mortalities worldwide. Patients with advanced cancers (stage IV) receive palliative care with minimal possibility of achieving complete remission. Antibody-based therapeutic modalities are capable of targeting tumors that are confined to a particular location but are ineffective in targeting distant secondary tumors.
View Article and Find Full Text PDFPhotodynamic/photothermal therapy (PDT/PTT) that deploys a near-infrared responsive nanosystem is emerging to be a promising modality in cancer treatment. It is highly desirable to have a multifunctional nanosystem that can be used for efficient tumor targeting and inhibiting metastasis/recurrence of cancer. In the current study, self-assembled chlorophyll-rich fluorosomes derived from were developed.
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