Publications by authors named "Nazdar Adil-Gholam"
Article Synopsis
- Research shows a correlation between the gut microbiome and the effectiveness of cancer immunotherapy, specifically for CAR T cell patients.
- The study identifies pentanoate, a metabolite from commensal bacteria, as a key factor that enhances patient survival by improving CAR T cell performance in challenging tumor environments.
- Findings suggest that incorporating microbial metabolites like pentanoate into CAR T cell manufacturing can exploit metabolic pathways and epigenetic changes to enhance treatment outcomes.
