Publications by authors named "Nazan Dolu"

Background: Internet gaming disorder (IGD) has become increasingly prevalent worldwide and is recognized as a significant public health concern because of its negative consequences on individuals mental and physical health, social relationships, academic performance and overall well-being. While research on IGD has gained significant momentum in the past decade, the neural substrates underlying this disorder remains unclear. This study aims to investigate resting-state cortical activation in male subjects with IGD using a concurrent functional near infrared spectroscopy (fNIRS) and electroencephalography (EEG) hybrid system.

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Background: Boron effects on reproduction and growth have been extensively studied in animals. Electrodermal activity (EDA) reflects the activity of eccrine sweat glands stimulated by the release of acetylcholine from sympathetic nerves.

Aim: In the presen study, it was aimed to examine the effect of boron, which was turned into cream, on sweat glands.

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Article Synopsis
  • * In a study of 45 children with ASD, six specific microRNAs were found at significantly lower levels in their serum compared to healthy controls, and similar patterns were observed in unaffected parents and siblings.
  • * Mouse models of ASD also showed a consistent microRNA profile, suggesting a genetic link and potential for early identification of ASD, which could lead to better diagnostic methods in the future.
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Divided attention is defined as focusing on different tasks at once, and this is described as one of the biggest problems of today's society. Default examinations for understanding attention are questionnaires or physiological signals, like evoked potentials and electroencephalography. Physiological records were obtained using visual, auditory, and auditory-visual stimuli combinations with 48 participants-18-25-year-old university students-to find differences between sustained and divided attention.

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Introduction: Attention-deficit/hyperactivity disorder (ADHD) is associated with a broad range of neuropsychological impairments that are attenuated with methylphenidate (MPH) treatment. The aim of this study was to determine how MPH effects attentional functioning in terms of reaction time (RT) in ADHD.

Methods: Eighteen pre-medicated ADHD children (7 to 12 years old) and eighteen gender matched normal controls (7 to 12 years old) were included in the study.

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The effect of vitamin E intake on spatial learning and working memory performances of young rats has been investigated in the Morris water maze and locomotor activity has been assessed by an open-field test. A total of 45 young male Wistar albino rats aged two months were divided into three equal groups: control, olive oil, and vitamin E groups. These groups were treated for 30 days with a once daily intraperitoneal injection.

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Carnosine is a dipeptide formed of the amino acids β-alanine and histidine. Only a limited number of studies have examined the effects of carnosine on sympathetic nerve activation and anxiety. The present study was undertaken to determine the dose-related effects of carnosine on anxiety in the elevated T-maze test (ETM) with electrodermal activity (EDA).

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The purpose of the study is to evaluate Auditory Evoked Potentials (AEPs) in patients with hyperthyroidism and to compare their frequency components with those of healthy subjects. In this study the AEPs in hyperthyroidism were studied both in time and frequency domains rather than studying just in the time domain by peak scoring. This paper presents a method for filtering auditory oddball standard and target AEPs by using singular spectrum analysis (SSA) and feature extraction in the frequency domain via spectral analysis.

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Aim: Behavioral and mental changes may occur in people exposed to cold stress by decreasing their work efficiency and their mental capacity while increasing the number of accidents on the job site. The goal of this study was to explore the effect of cold stress in spatial learning performance excitability and LTP.

Materials And Methods: Three to four month old rats were randomly divided into four groups to form a control group and a cold stress group for each sex.

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Introduction: Electrodermal activity (EDA) is an electrical activity of eccrine sweat gland stimulated by the sympathetic nervous system. Skin conductance level (SCL) is measured with EDA. SCL and sweat gland activity increase in emotional situations, such as high activation, attention or stress.

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Omega-3 fatty acid deprivation during development reduces performance in learning tasks, and dietary DHA supplementation improves learning ability and enhances long term memory in both young and old animals. However, little attention has been paid to the effect of maternal intake of Omega-3 fatty acids on hippocampal function in their pups. Randomly some of the pregnant dams were supplemented with Omega-3 essential fatty acid, others with tap-water, during pregnancy and breast-feeding by gavage daily.

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Background: Manipulating thyroid hormones has been shown to influence learning and memory. Although a large body of literature is available on the effects of thyroid hormone deficiency on learning and memory functions during developmental or adult-onset hypothyroidism, electrophysiological findings are limited. This limitation is especially notable with respect to thyroxine administration in adult, normothyroid animals.

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Some evidence suggests that sleep deprivation might impair synaptic plasticity and produce oxidative stress in the hippocampus. However it is not clear whether impairment of long-term potentiation depends on the oxidative stress evoked by sleep deprivation protocol. In this study we aimed to investigate the effects of a 21-day sleep deprivation period on long-term plasticity taking into account the stressful effect of sleep deprivation.

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Carnosine is a dipeptide synthesized by the carnosine synthetase from β-alanine and l-histidine. The well-known effects of carnosine may be related with mechanisms producing long-term potentiation which is one of the electrophysiological signs of memory. In the present study we aimed to investigate the effect of four different doses of carnosine on long-term potentiation in urethane-anesthetized rat.

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The objective of this study was to examine the effect of carnosine on the hippocampal-dependent learning in perforant pathway/dentate gyrus synapses. The experiments were carried out on adult rats. A bipolar stimulating electrode was placed to the medial perforant path and a double-barrel glass micropipette was placed in the dentate gyrus as the recording electrode.

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During the month of Ramadan, practicing Muslims abstain from eating and drinking from sunrise to sunset. We aimed to investigate the effect of Ramadan fasting on arousal and continuous attention. The electrodermal activity and cancellation test of students were measured in fasting and non-fasting conditions after the conclusion of the Ramadan fast period.

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We investigated effect of glycine on anxiety at different doses using electrodermal activity and an elevated-plus maze. A single dose of glycine was injected intraperitoneally into three different groups of mice at 250 mg/kg, 750 mg/kg, and 1250 mg/kg. The anxiety scores with the elevated-plus maze, consisting of two open arms and two enclosed arms, were measured 30 minutes after injection.

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This study investigated the relationship between hyperglycemia and electrodermal activity (EDA) parameters in streptozotocin (STZ) induced diabetic rats. The article evaluates the course of development of neurophysiological alterations in the peripheral nervous system in diabetic rats through EDA. Rats were made diabetic using a moderate dose of STZ (DI) and high dose (DII).

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Unlabelled: Recent electrophysiological studies on autonomic dysfunction in vitiligo patients show an autonomic dysfunction as measured by absent sympathetic skin response (SSR). Nothing is known about the reversibility of these autonomic parameters with treatment. The present study examined how Electrodermal Activity (EDA) parameters were affected from vitiligo illness before PUVA therapy and whether any electrophysiological gains acquired from PUVA therapy would influence the progression of the condition itself.

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In this study, using auditory sequences, the authors designed an examination with three phases of stimulus-driven attention that is based on the possibility that involuntarily time shifts of attention are caused by nonunique stimulus properties. The purpose was to investigate whether attending and temporal expectancies are influenced by stimulus's properties and by sex. In each phase, an auditory stimulus train was presented, and the participant was asked to tap rhythmically in order to anticipate every fifth stimulus (or, in the third phase, the lack of it).

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Several previous studies have reported that cigarette smoking enhances performance of cognitive processing. These enhancements are generally attributed to the pharmacological effects of nicotine, while there is some debate whether the effects of smoking/nicotine are a result of recovery from abstinence. Evoked potentials (EPs) and event related potentials (ERPs) of the brain have been applied as an index of information processing in a wide variety of normal and cognitive impaired subjects.

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Central sensory filtering processes can be demonstrated using a paired stimulus paradigm. Normal humans show a diminished, vertex-recorded mid-latency (50 ms) of auditory evoked potential to the second of paired clicks (0.5 s apart), a phenomenon termed as auditory gating.

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This study aimed to investigate the usefulness of auditory evoked potentials (AEPs) in rats. To this end, N1, P2 latencies, and the N1-P2 amplitude of responses to different acoustic stimuli from rats, which were implanted with permanent electrodes in the inferior colliculus (IC), were evaluated and used to demonstrate the frequency characteristics of IC region. Permanent electrodes were implanted in IC regions of 7 male albino rats by the stereotaxic method.

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