A carbon fiber modified with tin oxide/graphitic carbon nitride as an electrochemical indirect competitive immuno-sensor for ultrasensitive aflatoxin M detection.

The importance of developing multifunctional nanomaterials for sensing technologies is increasing with the arrival of nanotechnology. In this study, we describe the introduction of novel nanoprobe electro-active material into the architecture of an electrochemical immuno-sensor. Based on the electrochemical immuno-sensor, functionalized tin oxide/graphitic carbon nitride nanocomposite (fSnO/g-CN) was synthesized and then analyte specific anti-aflatoxin M monoclonal antibody (AFM-ab) combined to form an electro-active nanoprobe (fSnO/g-CN/AFM-ab).

Unleashing the synergistic effect of promising fungicides: a breakthrough solution for combating powdery mildew in pea plants.

Pea powdery mildew, caused by , is a major limitation to global pea production. The emergence of fungicide-resistant pathogen populations due to frequent and injudicious pesticide application highlights the importance of exploring the synergistic properties of fungicide combinations. This study investigated the efficacy of difenoconazole, thiophanate-methyl, and sulfur, both individually and in mixtures, against powdery mildew and assessed the interaction types between these fungicides.

Multi-temporal image analysis of wetland dynamics using machine learning algorithms.

Wetlands play a crucial role in enhancing groundwater quality, mitigating natural hazards, controlling erosion, and providing essential habitats for unique flora and wildlife. Despite their significance, wetlands are facing decline in various global locations, underscoring the need for effective mapping, monitoring, and predictive modeling approaches. Recent advances in machine learning, time series earth observation data, and cloud computing have opened up new possibilities to address the challenges of large-scale wetlands mapping and dynamics forecasting.

SAR image integration for multi-temporal analysis of Lake Manchar Wetland dynamics using machine learning.

The Manchar Lake wetland complex, Pakistan's largest freshwater-lake, faces unprecedented ecological challenges amidst climate change and human pressures, necessitating urgent, data-driven conservation strategies. This study employs cutting-edge multi-sensor remote sensing techniques to quantify and analyze the dynamic changes in this critical ecosystem from 2015 to 2023, aiming to provide a comprehensive understanding of wetland dynamics for informed management decisions. Integrating Sentinel-1 Synthetic Aperture Radar (SAR) and Sentinel-2 multispectral imagery, we assessed changes in wetland extent, vegetation health, and land-use patterns using spectral indices and topographic data.

The association between aerobic capacity and spinal curvature and mobility in young soccer players.

Background: There is a lot of research in terms of injuries and performance in football and nowadays aerobic capacity, spinal posture and mobility have been taken into consideration separately in terms of performance. Considering from a biomechanical perspective, we thought spinal curvature and mobility may affect aerobic performance and investigated the relationship between them.

Research Question: Do young soccer players' segmental spinal curvature and mobility affect their aerobic capacity and maximal exercise performance?

Methods: Thirty-four young league players (mean age 16.

Intelligent computing framework to analyze the transmission risk of COVID-19: Meyer wavelet artificial neural networks.

The optimum control methods for the epidemiology of the COVID-19 model are acknowledged using a novel advanced intelligent computing infrastructure that joins artificial neural networks with unsupervised learning-based optimizers i.e., Genetic Algorithms (GA) and sequential quadratic programming (SQP).

A field-portable electrochemical immunosensor based on a multifunctional AgO/g-CN@MA-DBB covalent organic framework receptor interface for single-step detection of aflatoxin M in raw milk samples.

Aflatoxin M (AFM), a hydroxylated metabolite of aflatoxin B (AFB), contaminates milk and dairy products from livestock ingestion of feed contaminated with a species of . As AFM is a Group-II B carcinogen, it is indispensable to develop novel, easy-to-handle, sensitive, portable and cost-effective strategies for its detection. Herein, a covalent organic framework (COF)-based electroactive nanocomposite, AgO/g-CN-COOH@MA-DBB-COF (silver oxide/carboxy-functionalized graphitic carbon nitride@melamine-dibromo butane COF), is designed to serve as a multifunctional receptor surface.

A multifunctional N-GO/PtCo nanocomposite bridged carbon fiber interface for the electrochemical aptasensing of CA15-3 oncomarker.

The development of integrated analytical devices is crucial for advancing next-generation point-of-care platforms. Herein, we describe a facile synthesis of a strongly catalytic and durable Nitrogen-doped graphene oxide decorated platinum cobalt (NGO-PtCo) nanocomposite that is conjugated with target-specific DNA aptamer (i-e. MUC1) and grown on carbon fiber.

Pre-clinical studies comparing the anti-inflammatory potential of artemisinic compounds by targeting NFκB/TNF-α/NLRP3 and Nrf2/TRX pathways in Balb/C mice.

Artemisinin, artemether, artesunate, and dihydroartemisinin are renowned for their antimalarial potential. The current study aims to repurpose the above-mentioned artemisinic compounds (ACs) by conducting an intercomparison to evaluate their antiinflammatory potential (AIP). In order to develop potential candidates for the evaluation of AIP of ACs (50 and 100 mg/kg BW), carbon tetrachloride (1ml/kg body weight (BW)) was administered intraperitoneally to BALB/c mice.

Investigation of the psychometric properties of "exercise Benefits/Barriers scale" in Turkish patients with rheumatoid arthritis.

Background: Rheumatoid arthritis (RA) is a chronic systemic disease accompanied by several symptoms and functional disabilities. Physical activity (PA) is crucial for disease management and patients' perception of exercise is essential for a rehabilitation plan.

Purpose: This study aims to examine the psychometric properties of the Exercise Benefits/Barriers Scale (EBBS) that is frequently used in previous studies in the RA population.

Phytogenic-Mediated Zinc Oxide Nanoparticles Using the Seed Extract of and Its Integrated Potency against Multidrug Resistant Bacteria.

In the current research study, zinc oxide nanoparticles (ZnO-NPs) were synthesized via a green synthesis technique using the seed extract of . The study further intended to evaluate the potential synergistic effects of ZnO-NPs with antibiotics against multidrug resistant (MDR) bacteria. It was observed that seed extracts obtained by -hexane and methanolic solvents revealed the presence of constituents, such as tannins, flavonoids, and terpenoids.

Associations of Upper-Extremity Exercise Capacity and Grip Strength With Cognitive Domains in Patients With COPD.

Background: Cognitive impairment (CI), which has been reported in COPD, has been related to physical performance. However, the association between CI and upper-extremity functions is unknown. We aimed to compare upper-extremity exercise capacity and grip strength between subjects with COPD with and without CI and to determine the relationship of upper-extremity functions with specific cognitive domains.

Investigation of the relationship between spinal posture and mobility to respiratory muscle strength and pulmonary functions in unilateral breast cancer surgery survivors: a cross-sectional study.

Purpose: Despite the research on structural and functional changes that may occur in breast cancer survivors, no study has investigated the relationship between spinal characteristics and the respiratory system. Therefore, we aimed to investigate the relationship between spinal posture and mobility to respiratory muscle strength and pulmonary functions in breast cancer patients who have completed their treatment METHODS: This cross-sectional study included 38 female breast cancer surgery survivors. Participants underwent the following evaluations: Chest wall mobility with a tapeline; postural assessments (spinal curvature, spinal mobility, and spinal inclination) with a non-invasive, computer-assisted electromechanical device; and pulmonary function test and respiratory muscle strength with a portable digital spirometer device.

Investigation of factors associated with static and dynamic balance in early-stage lung cancer survivors.

Purpose: Balance impairment and falls are common among patients after cancer treatment. This study aimed to compare static and dynamic balance functions in lung cancer survivors (LCS) and healthy controls and to investigate the factors related to balance in LCS.

Methods: Cross-sectional data were collected from lung cancer patients whose treatment had been completed within the previous 3 months (n = 60) and age and gender-matched healthy controls (n = 60).

Comparison of Self-Efficacy and Problem-Solving Skills Between Women with Asthma and Healthy Controls: A Cross-Sectional Study.

Objective: Problem-solving skills and self-efficacy are among the topics that are frequently investigated in people with various chronic conditions. However, there are limited studies on asthma patients. Our study aims to compare self-efficacy and problem-solving skills in asthma patients and healthy controls.

Recent innovations in microplastics and nanoplastics removal by coagulation technique: Implementations, knowledge gaps and prospects.

Recently, microplastics (MPs) and nanoplastics (NPs) contamination is a worldwide problem owing to the immense usage of plastic commodities. Thus, the environmental risks by MPs and NPs demand the application of innovative, efficient, and sustainable technologies to control the pollution of plastic particles. Regarding this, numerous technologies, including adsorption, coagulation, filtration, bioremediation, chemical precipitation, and photocatalysis, have been engaged to eradicate MPs and NPs from contaminated waters.

Comparing Physical Activity and Quality of Life of Caregivers of Children With Physical Disabilities and Typically Developing Children.

There are conflicting reports of the level of physical activity (PA) and its relationship to quality of life (QoL) among caregivers of children with physical disabilities (CwPD). In this cross-sectional study, we aimed to compare the PA levels and QoL of two groups of caregivers - a CwPD group and caregivers of typically developing children (CwTD). We included 32 family caregivers in the CwPD group (22 women, 10 men; age = 42.

Diversification of the Islamic stock market, Bitcoin, and Bullions in response to the Russia-Ukraine conflict and the COVID-19 outbreak.

This study investigates the interconnectedness of the Islamic stock market, Bullion, and Bitcoin as diversifiers for portfolios, exploring their role as hedges and safe havens. The analysis covers the period from January 2015 to December 2022, with a particular focus on the influence of the COVID-19 pandemic and the Russia-Ukraine War on the MSCI World Islamic Index, bullions (Gold, Silver, Platinum, Nickel, Palladium, and Aluminium), and Bitcoin, employing a time-varying parameter vector autoregression (TVP-VAR) model. During crisis periods, our findings reveal that the transmission and reception of shocks among these assets varied, with a heightened level of co-movement observed during the pandemic and war periods.

Preparation and characterization of single perovskite microplates and its sunlight assisted photodecolorization activity, validated by response surface methodology.

Perovskites overtaking simple metal oxides as solar light harvesting material due to their excellent photocatalytic efficiency and superior stability. An efficient visible light responsive, KBaCuO single perovskites oxides (SPOs) photocatalyst was fabricated by a facile hydrothermal method. The fabricated SPOs was characterized by various techniques.

Fabrication of Novel Omeprazole-Based Chitosan Coated Nanoemulgel Formulation for Potential Anti-Microbia; In Vitro and Ex Vivo Characterizations.

Infectious diseases remain inevitable factors for high mortality and morbidity rate in the modern world to date. Repurposing is a novel approach to drug development has become an intriguing research topic in the literature. Omeprazole is one of the top ten proton pump inhibitors prescribed in the USA.

Protects Rats against CCl-Induced Hepatic Injuries through Modulation of an Unfolded Protein Response Pathway and Pro-Inflammatory Intermediates.

Liver fibrosis is a major pathological feature of chronic liver disease and effective therapies are limited at present. The present study focuses on the hepatoprotective potential of . against carbon tetrachloride (CCl)-induced liver damage in rats.