Isolation and crystallization of copper resistance protein B (CopB) from Acinetobacter baumannii.

Acinetobacter baumannii (A. baumannii) is an opportunistic, Gram-negative human pathogen, which is predominantly found in hospital patients. Its antimicrobial resistance is escalating, leading to less efficient treatments, and an increasing interest in identifying new therapeutic drugs.

Living With Multiple Sclerosis: The Rainbow of Inspiring Experiences and Resilience in the Face of the Disease.

Introduction: Multiple sclerosis (MS), a leading cause of disability in young adults worldwide, including in Iran, affects their whole life so common care is no longer effective. In this regard, context-based approaches should be considered for a holistic care delivery that accords with the patients' inputs. We aimed to explore patients' understanding of MS and their personal experiences of living with this disease.

Improving the quality of clinical training in maternal and neonatal health in undergraduate nursing students: a participatory action research.

Background: Improving the quality of clinical training is synonymous with accomplishing nursing education goals and improving the quality of nursing care. This study aimed to improve the quality of clinical training in Maternal and Neonatal Health (MNH) in nursing students.

Methods: This action research was conducted in two cycles from June 2017 to June 2018.

Investigating the relationship between missed/rationed nursing care and organizational commitment in Iranian nurses.

Background And Objective: The primary objective of the nursing profession is to provide comprehensive and appropriate nursing care that meets the individual needs of patients. However, instances of missed/rationed nursing care can jeopardize the delivery of complete and safe healthcare, potentially putting patients' lives at risk. The level of organizational commitment demonstrated by nurses is likely to impact various personnel and organizational factors.

Impaired health in working children: a critical ethnography.

Child labor is one of the important social issues that deprive children of many fundamental rights, and make them face many problems and consequences, including health problems. Thus, this study was conducted with the aim of examining the health of working children in Tehran. This is an ethnographic study that was conducted using Carspecken's approach and was completed in 2022.

Outcomes of professional misconduct by nurses: a qualitative study.

Background: Professional misconduct by nurses is a critical challenge in providing safe quality care, which can lead to devastating and extensive outcomes. Explaining the experiences of clinical nurses and nursing managers in this regard using an in-depth qualitative method can be beneficial. This study was conducted with the aim of explaining the experiences of nurses regarding the outcomes of professional misconduct.

Nurses' Experiences of Practical Challenges Associated with Nurses' Prescription: A Qualitative Study.

Background: Because nurse prescription has numerous benefits for the health systems, in many countries around the world, nurses are given the right to prescribe medication. In Iran, the role of nurses in prescription drugs is not well understood, and nurses face various challenges in this regard.

Materials And Methods: A qualitative content analysis methodology based on the Graneheim and Lundman model was used.

The effectiveness of agomelatine on headache severity and frequency in episodic migraine without aura; a parallel randomized controlled trial study.

Background: Migraine is a headache disorder that affects public health and reduces the patient's quality of life. Preventive medication is necessary to prevent acute attacks and medication overuse headaches (MOH). Agomelatine is a melatonin antagonist.

Design and validation of the presenteeism scale in nursing.

Background: The instruments used to measure presenteeism are all flawed and only incompletely measure the concept of presenteeism in employees of the general population. As a result, the concept of presenteeism is not measured, and in most of these instruments, the population for which the instrument has been developed differs from the nursing population. The present research was conducted to design and validate the instrument for evaluating presenteeism in nursing.

The nurses' perception of the factors influencing professional misconduct: A qualitative study.

Background: Professional misconduct undermines safe and quality care; however, little is known about its nature and influential factors.

Aim: This study aimed to explain the factors influencing professional misconduct in nurses.

Research Design: This qualitative study was conducted using the conventional content analysis method.

Ethical Challenges to the Self-care of Nurses during the Covid-19 Pandemic.

Background: The emerging working conditions triggered by the COVID-19 pandemic have imposed numerous ethical challenges on the nurses, which, in turn, can negatively impact the nurses' physical and mental health, and thus their work performance through intensifying negative emotions and psychological pressures.

Aim: The purpose of this study was to highlight the nurses' perceptions of the ethical challenges that they faced regarding their self-care during the COVID-19 pandemic.

Research Design: A qualitative, descriptive study with a content analysis approach.

Nurses' safety-related organisational challenges during the COVID-19 pandemic: A qualitative study.

Aim: To explore nurses' perspectives on and experiences of safety-related organisational challenges during the coronavirus disease 2019 (COVID-19) outbreak by Iranian nurses.

Background: In different clinical contexts, nurses face numerous organisational challenges threatening their safety because of the COVID-19 pandemic.

Introduction: Exploring nurses' perceptions towards safety-oriented organisational challenges might inform nurse managers, healthcare managers, educators and policymakers on the priorities that should be considered to increase organisations' readiness and safety.

Principles to recover copper-conducting CTR proteins for the purpose of structural and functional studies.

Transition metals such as copper and zinc are essential elements required for the survival of most organisms, from bacteria to humans. Yet, elevated levels of these elements are highly toxic. The Copper TRansporter protein family (CTRs) represents the only identified copper uptake proteins in eukaryotes and hence serves as key components for the maintenance of appropriate levels of the metal.

Effect of Home Care Program on Re-hospitalization in Advanced Heart Failure: A Clinical Trial.

Background: Heart failure is the leading cause of readmission in all medical and surgical patients. Home care studies have reduced hospitalization in heart failure. This study aimed to investigate the effect of home care program on readmission in advanced heart failure.

Ways To Enhance Blood Transfusion Safety: A Systematic Review.

Aim: Blood product administration is a vital and possibly life-threatening issue that may increase the risk of clinical damage in patients. This review aims to provide a comprehensive review of the ways to improve blood transfusion safety.

Method: In order to conduct this systematic review, electronic databases, including PubMed/MEDLINE, EMBASE, Web of Science, Cochrane CENTRAL, Scopus, and Google Scholar, were searched for data of the last 30 years using keywords including patient safety, blood transfusion, risk management, safety management, and transfusion reaction.

Microfluidic-Derived Detection of Protein-Facilitated Copper Flux Across Lipid Membranes.

Measurement of protein-facilitated copper flux across biological membranes is a considerable challenge. Here, we demonstrate a straightforward microfluidic-derived approach for visualization and measurement of membranous Cu flux. Giant unilamellar vesicles, reconstituted with the membrane protein of interest, are prepared, surface-immobilized, and assessed using a novel quencher-sensor reporter system for detection of copper.

Blinding and Its Quality in Clinical Trials Conducted on Patients with Breast Cancer: A Systematic Review.

Background: Blinding is one of the critical criteria of clinical trials that prevents probable bias. Judgment regarding results of an intervention significantly depends on the quality of such studies, one of which is blinding. This study aimed to investigate blinding and its quality in clinical trials in patients with breast cancer.

Caring for Patients in a Coma Following a Traumatic Brain Injury in Iran.

The study described here is the process of caring for patients in a coma following a traumatic brain injury (TBI) in Iran. The data that were analyzed come from in-depth semistructured interviews of 20 key participants and associated memos and field notes. The MAXQDA 10 qualitative analysis software was used to assist with the coding of the data.

Clinical manifestation, laboratory and radiology finding, treatment and outcomes of COVID-19: A systematic review and meta-analysis.

Background: Since December 2019, coronavirus (COVID-19) spread throughout the world. The high rate of infection and its unknown nature led specialists to report the condition of patients. The aim of this study is to systematically review of symptoms, laboratory and radiologic findings, treatment, and outcomes of patients with COVID-19.

The nurse without a nurse: the antecedents of presenteeism in nursing.

Background: Presenteeism describes the state in which staff who lack the conditions for being present at work and need rest and leave for various reasons (such as illness, low spirits, fatigue, etc.) are present at the workplace. Due to the lack of knowledge about the antecedents of presenteeism in nurses and the context-based nature of this concept, the present study was conducted to explain the reasons for presenteeism in nurses.

Patients' Experiences of Life Challenges After Liver Transplantation: A Qualitative Study.

Patients experience a new life with different challenges after liver transplantation (LT). Identifying these challenges can facilitate the improvement of their quality of life. This study aimed to explore patients' experiences of post-LT life challenges.

Being parent of a child with congenital heart disease, what does it mean? A qualitative research.

Background: Childbirth is one of the invaluable human experiences and is associated with parental happiness. However, when a child is born with congenital heart disease, it creates emotional and mental distress. As a result, it changes the parents' response to their child birth.

Taking care experiences of improved comatose patients with traumatic brain injury and their families.

Introduction: The most prominent causes of coma are traumatic brain injuries (TBIs), which have high incidence. However, little research about the caring aspects of these patients has been done, and the notion of caring experiences is unknown. Therefore, this study was conducted to describe the care-taking experiences of coma patients and their families during and after treatment.

Experiences of nurses within a nurse-led multidisciplinary approach in providing care for patients with diabetic foot ulcer.

Background And Aims: Diabetic foot ulcers require special attention due to their complex and chronic nature and special care and the Nurse-led approach has emerged in the current situation in response to the increasing need for health care as a way to treat chronic patients and provide them with ongoing care. Providing this specialized duty in nursing can be promoted and enhanced the professional independence of nurses and presents challenges. This study has been conducted to make an understanding of the nurses' experiences about their participation in a nurse-led multidisciplinary team to providing care for patients with Diabetic Foot Ulcer.