Characterization of clinical trials in Ecuador and their association with disease burden: Are there research gaps?

This study offers a detailed analysis of clinical trials conducted in Ecuador from 2010 to 2022 to assess alignment with the country's disease burden as indicated by the Global Burden of Disease study. Utilizing data from five registries, including ARCSA and Clinicaltrials.gov, we analyzed characteristics and coverage of 75 CTs after removing duplicates and ineligible studies.

[Spatial distribution of Echinococcus granulosus sensu lato genotypes in the american continent].

Background: Knowledge of the distribution cystic is required for its territorial control.

Aim: To describe the spatial distribution of Echinococcus granulosus sensu lato genotypes by host in the American continent.

Material And Methods: A systematic review of studies from the American continent, related to genotypes of the E.

PROTEOMIC PROFILE OF ECHINOCOCCUS GRANULOSUS: A SYSTEMATIC REVIEW.

Cystic echinococcosis is a zoonotic disease caused by the larval stage of Echinococcus granulosus. This affliction is an endemic worldwide condition that represents a neglected parasitic disease with important socioeconomic repercussions. Proteomic characterization of larval and adult stages of E.

Echinococcus granulosus sensu lato Genotypes in Different Hosts Worldwide: A Systematic Review.

Introduction: The aim of this study was to develop a synthesis of the evidence available regarding verified E. granulosus sensu lato (s.l.

The hemodynamic effects of diazepam versus dexmedetomidine in the treatment of alcohol withdrawal syndrome: A randomized clinical trial.

Background: Dexmedetomidine (DEX) is an alpha-2 adrenergic drug used for short sedation and as an alternative to diazepam (DZP) in the treatment of alcohol withdrawal syndrome (AWS).

Purpose: This study aims to compare the hemodynamic effect of DZP versus DEX on heart rate (HR) and blood pressure in patients with AWS.

Methods: Prospective randomized clinical trial that includes 40 patients with AWS from Mérida, Yucatán, México.

[Necrotizing amebian colitis, case report].

Background: Amebiasis has been defined by World Health Organization (WHO) and Pan American Health Organization (PAHO) as the infection with Entamoeba histolytica regardless of symptoms. Necrotizing amoebic colitis is a rare clinical form of amebosis that is associated with high morbidity and mortality.

Case Report: We present a 68-years-old-female patient with necrotizing amoebic colitis with multiple perforations who survived after right hemicolectomy with ileus-transverse anastomosis.

[Echinococcus granulosus genotypes verified in human hydatid disease around the world. Systematic review].

Background: The evidence regarding genotypic characteristics of Echinococcus granulosus infection in humans worldwide is scarce.

Aim: To develop a synthesis of the available evidence regarding genotypes of E. granulosus verified in humans worldwide.

Echinococcus Granulosus Haplotypes in the Scientific Literature.

Echinococcus granulosus (Eg) is a parasite causing an incidental infection in humans. The disease can be observed as a hydatid cyst in the liver and lungs and is found in dogs and wolves as definitive hosts. It is considered a neglected infectious disease which has rarely been studied in Mexico1.

[Clinical, serological and polymerase chain reaction follow-up of a family with brucellosis].

Introduction: Human brucellosis diagnosis is based on isolation of Brucella spp. from blood or tissue cultures with a positivity rate of 40-70% and serology techniques are used as complementary tools; recently molecular biology diagnostic techniques have been developed intending to optimize the etiological confirmation.

Aim: The main objective of this work was to compare the polymerase chain reaction (PCR), against serological diagnostic tests during the clinical follow-up of a family presenting brucellosis.