Publications by authors named "Nayara Araujo Dos Santos"
J Agric Food Chem
June 2024
Article Synopsis
- A series of 19 novel eugenol derivatives featuring a 1,2,3-triazole structure were synthesized using a copper(I)-catalyzed reaction, aimed at enhancing antifungal activity.
- Several triazole compounds were tested for their effectiveness against the fungus causing papaya anthracnose, with four compounds showing significant reductions in mycelial growth by over 80%.
- Molecular docking studies revealed how these derivatives bind to the CYP51 enzyme, suggesting that their antifungal properties may stem from blocking substrate access, paving the way for environmentally friendly antifungal agents.
J Am Soc Mass Spectrom
April 2021
Article Synopsis
- MALDI IMS is a technique used to identify and map the distribution of molecules in samples while keeping their natural structure intact, but its application on the spatial distribution of alkaloids in coca leaves is not well-studied.
- This research utilized MALDI(+)FT-ICR IMS to identify and analyze alkaloids on coca leaf surfaces, testing different matrices and finding that 2,5-dihydroxybenzoic acid (DHB) was the most effective at a concentration of 2 mg·mL.
- The study also examined the inner leaf tissue, revealing the presence of alkaloids and flavonoids, while washing the leaves with various organic solvents did not enhance ionization efficiency.
