Dissimilar Anxiety-like Behavior in Prepubertal and Young Adult Female Rats on Acute Exposure to Aluminium.

Background: Puberty is a developmental transition in which an estrogenic surge occurs, mediating the release of xenoestrogens, like aluminium. Aluminium's effect on anxiety in rodents at the different developmental stages is inconsistent.

Aims: This study aimed at investigating the effect of the metalloestrogenic property of aluminium on anxiety-like behavioral changes in prepubertal and young adult female rats.

Comment on Samulewski et al. Magnetite Synthesis in the Presence of Cyanide or Thiocyanate under Prebiotic Chemistry Conditions. 2020, , 34.

Samulewski et al. (2020) [..

Effectiveness of community-based treatment programs for treatment of uncomplicated severe acute malnourished children aged 6-59 months using locally produced nutrient dense foods: protocol for a multicentric longitudinal quasi-experimental study.

Background: Severe acute malnutrition (SAM) is a major underlying cause of mortality among children. Around one third of the world's acutely malnourished children live in India. The WHO recommends community-based management of acute malnutrition (CMAM) for managing children with SAM.

Release Mechanisms and Practical Percolation Threshold for Long-acting Biodegradable Implants: An Image to Simulation Study.

The development of long-acting drug formulations requires efficient characterization technique as the designed 6-12 months release duration renders real-time in vitro and in vivo experiments cost and time prohibitive. Using a novel image-based release modeling method, release profiles were predicted from X-Ray Microscopy (XRM) of T0 samples. A validation study with the in vitro release test shows good prediction accuracy of the initial burst release.

Efficacy and Safety of Bioresorbable Vascular Scaffold (BVS) - Absorb in Acute Myocardial Infarction - A 45 Month Follow Up Study.

Aim: Bioresorbable vascular scaffolds (BVS) over the years have emerged as a new treatment option in coronary revascularization. There is a limited data on the use of these novel devices in patients with acute myocardial infarction (AMI). The purpose of this study was to evaluate the safety feasibility and efficacy of BVS implantation in patients with AMI.

Adaptive sports for promoting physical activity in community-dwelling adults with stroke: A feasibility study.

Background: Despite proven health benefits of regular participation in physical activities (PA), adults with stroke fail to achieve recommended levels of PA. Sports being an enjoyable activity is more likely to encourage participation. Therefore, the objectives of the present study are i) to develop and test the feasibility of adaptive sports for promoting PA and Quality of Life (QoL) in community-dwelling adults with stroke, and ii) to explore the participants perception and experiences of playing adaptive sports.

Major neurological complications following central neuraxial blockade - A multicentre pilot study in Aurangabad city (MGMA CNB Study).

Background And Aims: Incidence of major neurological complications following central neuraxial blockade (CNB) in India is not known. This information is essential for explaining risk preoperatively to patients and for medico-legal purposes. This study was undertaken to assess feasibility (recruitment process, protocol adherence, resources mobilisation, data management and evaluation of scientific outcome) for planning multicentric studies on major neurological complications following CNB at state/national level.

Employing Multimodal Machine Learning for Stress Detection.

In the current information age, the human lifestyle has become more knowledge-oriented, leading to sedentary employment. This has given rise to a number of health and mental disorders. Mental wellness is one of the most neglected, however crucial, aspects of today's fast-paced world.

Standardization of process protocol for isolation of starch from mango kernel and its characterization.

Background: The major by-products of mango processing are the seeds, which represent approximately 15-20% of the fruit. The process protocol for isolation of starch from mango kernel was standardized based on starch yield, starch purity and colour values using centrifugation and chemical method. Optimized starches obtained from both methods were further investigated for estimation of functional properties and were characterized through Fourier transform infrared spectroscopy, scanning electron microscopy, X-ray diffraction, differential scanning calorimetry and pasting properties analysis.

2D Position-Sensitive Hybrid-Perovskite Detectors.

Hybrid organic-inorganic perovskites (HOIPs) have emerged as a versatile class of semiconductors for numerous optoelectronic applications. Here, we demonstrate light-excitation-dependent two-dimensional (2D) position-sensitive detectors (PSDs) using a mixed-phase perovskite, FACsPb(IBr), as the active semiconductor, incorporated within a five-terminal device geometry. The light-induced lateral photovoltage, which is initiated by selective charge transfer across the metal-perovskite barrier interface, is utilized to achieve the excitation-position-dependent electric response.

Surgical Site Infections in patients undergoing major oncological surgery during the COVID-19 paNdemic (SCION): A propensity-matched analysis.

Background And Objectives: There are reports of outcomes of elective major cancer surgery during the COVID-19 pandemic. We evaluated if reinforcement of hand hygiene, universal masking, and distancing as a part of pandemic precautions led to a decrease in the incidence of surgical site infections (SSIs) in major oncologic resections.

Methods: Propensity score matching using the nearest neighbor algorithm was performed on 3123 patients over seven covariates (age, comorbidities, surgery duration, prior treatment, disease stage, reconstruction, and surgical wound type) yielding 2614 matched (pre-COVID 1612 and COVID 1002) patients.

Perfluoroalkyl substances exposure and immunity, allergic response, infection, and asthma in children: review of epidemiologic studies.

Background: Increased exposure to perfluoroalkyl substances (PFAS) potentially affects infant and childhood health through immunosuppression. Given rapidly evolving research on PFAS, it is important to comprehensively examine the impact of PFAS exposure among the pediatric population as new research becomes available due to potential fragility of the developing immune system.

Objectives: This review assessed the effects of PFAS fetal, infant and childhood exposures upon the development of immune function during early life stages.

Postoperative Pain Relief Following Lumbar Erector Spinae Plane Block in Patients Undergoing Percutaneous Nephrolithotomy: A Randomized Controlled Trial.

Objective: To test whether lumbar Erector Spinae Plane Block (ESPB) provides superior analgesia compared to placebo in patients undergoing Percutaneous Nephrolithotomy (PCNL), using reduction in postoperative opioid consumption, delay in rescue analgesia demand and reduction of pain scores as outcome measures.

Methods: 34 adult (18-60 years) ASA I and II patients undergoing unilateral PCNL were randomized into two groups (Bupivacaine and Saline) - both receiving ipsilateral ESPB at L1 vertebral level with either 20 ml 0.25% Inj.

Emerging Treatment Strategies for Diabetes Mellitus and Associated Complications: An Update.

The occurrence of diabetes mellitus (DM) is increasing rapidly at an accelerating rate worldwide. The status of diabetes has changed over the last three generations; whereas before it was deemed a minor disease of older people but currently it is now one of the leading causes of morbidity and mortality among middle-aged and young people. High blood glucose-mediated functional loss, insulin sensitivity, and insulin deficiency lead to chronic disorders such as Type 1 and Type 2 DM.

Successful noninvasive ventilation in a severely acidotic and hypercapnic comatose COVID-19 patient with multiple comorbidities: a case report.

Effective use of noninvasive ventilation in patients with chronic obstructive pulmonary disease is well-known. However, noninvasive ventilation in patients presenting with altered sensorium and severe acidosis (pH <7.1) has been rarely described.

"I'm Bored and I'm Stressed": A Qualitative Study of Exclusive Smokers, ENDS Users, and Transitioning Smokers or ENDS Users in the Time of COVID-19.

Background: To better understand the various influences of COVID-19 on tobacco use, we examined three different tobacco user groups using qualitative methods.

Methods: Ten online focus groups with 61 adults from the Atlanta, GA area were held in October-November 2020: four with exclusive smokers (n = 16), three with Electronic Nicotine Delivery System (ENDS) users (dual and exclusive, n = 22), and three with transitioning (recently quit or currently quitting) smokers and/or ENDS users (n = 23).

Results: Exclusive smokers reported smoking more frequently, driven by COVID-19-related stress, time at home, and boredom.

Outcomes of osteosarcoma, chondrosarcoma and chordoma treated with image guided-intensity modulated radiation therapy.

Background & Purpose: To evaluate the efficacy and toxicity of dose-escalated image guided-intensity modulated radiation therapy (IG-IMRT) in osteosarcoma (OGS), chondrosarcoma (CS) and chordoma (CH) of head and neck (H&N) and pelvis.

Methods And Materials: In this prospective non-randomized study, 65 patients of H&N or pelvic OGS (24), CS (7) and CH (34) mandating definitive or post-operative radiotherapy from May 2013 to December 2018 were included. Radiotherapy doses in definitive setting were 72.

Thiophene-fused boracycles as photoactive analogues of diboraanthracenes.

The construction of thiophene-fused analogues of diboraanthracenes with different aryl substituents through boron-mercury exchange followed by the nucleophilic replacement of the chlorines of dichlorodiboradithiophene 2 with Grignard reagents is reported. These diboradithiophenes exhibited unusual photophysical and electrochemical properties. They all undergo photoisomerisation, which can be traced using photophysical and H NMR spectroscopy studies.