spp. cause hundreds of millions of intestinal infections each year. They target the mucosa of the human colon and are an important model of intracellular bacterial pathogenesis.
View Article and Find Full Text PDFis an Escherichia coli pathovar that colonizes the cytosol of mucosal cells in the human large intestine. To do this, uses a Type III Secretion Apparatus (T3SA) to translocate several proteins into host cells. The T3SA and its substrates are encoded by genes of the virulence plasmid pINV or by chromosomal genes derived thereof.
View Article and Find Full Text PDFspp. are one of the leading causes of infectious diarrheal diseases. They are pathovars that are characterized by the harboring of a large plasmid that encodes most virulence genes, including a type III secretion system (T3SS).
View Article and Find Full Text PDFShigella spp. are enterobacteria that invade human colonic mucosal cells using their Type Three Secretion Apparatus (T3SA). Shigella spp.
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