Publications by authors named "Navoun Silue"

spp. cause hundreds of millions of intestinal infections each year. They target the mucosa of the human colon and are an important model of intracellular bacterial pathogenesis.

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is an Escherichia coli pathovar that colonizes the cytosol of mucosal cells in the human large intestine. To do this, uses a Type III Secretion Apparatus (T3SA) to translocate several proteins into host cells. The T3SA and its substrates are encoded by genes of the virulence plasmid pINV or by chromosomal genes derived thereof.

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spp. are one of the leading causes of infectious diarrheal diseases. They are pathovars that are characterized by the harboring of a large plasmid that encodes most virulence genes, including a type III secretion system (T3SS).

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Shigella spp. are enterobacteria that invade human colonic mucosal cells using their Type Three Secretion Apparatus (T3SA). Shigella spp.

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Article Synopsis
  • Enterobacteriaceae is a diverse group of Gram-negative bacteria, some of which are harmless residents in humans and animals, while others can cause serious diseases.
  • The review specifically discusses Salmonella, Escherichia, Shigella, and Yersinia, detailing the diseases they cause and the impact on human health.
  • It emphasizes the importance of animal models in studying how these bacteria cause disease and identifying genetic factors that affect a person's susceptibility to infections.
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