Effect of mitral isthmus block on development of atrial tachycardia following ablation for atrial fibrillation.

Background: Successful mitral isthmus (MI) ablation may reduce recurrence of atrial fibrillation (AF) and macro-reentrant atrial tachycardia (AT) after pulmonary vein isolation (PVI) for AF.

Objective: To determine if achieving bidirectional MI conduction block (MIB) during circumferential pulmonary vein ablation (CPVA) plus left atrial linear ablation (LALA) affects development of AT.

Methods: Sixty consecutive patients with persistent (n = 25) or paroxysmal (n = 35) AF undergoing CPVA plus LALA at the MI and LA roof were evaluated in a prospective, nonrandomized study.

Diagnosis and management of typical atrial flutter.

Typical atrial flutter (AFL) is a common atrial arrhythmia that may cause significant symptoms and serious adverse effects including embolic stroke, myocardial ischemia and infarction, and rarely a tachycardia-induced cardiomyopathy as a result of rapid atrioventricular conduction. As a result of the well-defined anatomic and electrophysiological substrate, and the relative pharmacologic resistance of typical AFL, radiofrequency catheter ablation has emerged in the past decade as a safe and effective first-line treatment. This article reviews the electrophysiology of typical AFL and the techniques currently used for its diagnosis and management.

Diagnosis and management of typical atrial flutter.

Can "past decade" be rephrased to refer to more specific years? Typical atrial flutter (AFL) is a common atrial arrhythmia that may cause significant symptoms and serious adverse effects, including embolic stroke, myocardial ischemia and infarction, and, rarely, a tachycardia-induced cardiomyopathy resulting from rapid atrioventricular conduction. As a result of the well-defined anatomic and electrophysiologic substrate and the relative pharmacologic resistance of typical AFL, radiofrequency catheter ablation has emerged since its first description in 1992 as a safe and effective first-line treatment. This article reviews the electrophysiology of typical AFL and techniques currently used for its diagnosis and management.

Prospective comparison of echocardiographic atrioventricular delay optimization methods for cardiac resynchronization therapy.

Background: Atrioventricular (AV) delay optimization can be an important determinant of the response to cardiac resynchronization therapy (CRT) in patients with medically refractory heart failure and a ventricular conduction delay.

Objectives: The purpose of this study was to compare two Doppler echocardiographic methods of AV delay optimization after CRT.

Methods: Forty consecutive patients (age 59 +/- 12 years) with severe heart failure, New York Heart Association class 3.

Randomized prospective trial of atrioventricular delay programming for cardiac resynchronization therapy.

Objectives: The purpose of this study was to determine if AV delay optimization with continuous-wave Doppler aortic velocity-time integral (VTI) is clinically superior to an empiric program in patients treated with cardiac resynchronization therapy (CRT) for severe heart failure.

Background: The impact of AV delay programming on clinical outcomes associated with CRT is unknown.

Methods: A randomized, prospective, single-blind clinical trial was performed to compare two methods of AV delay programming in 40 patients with severe heart failure referred for CRT.