Publications by authors named "Navilla Apu"
Background: the gold-standard diagnostic protocol (GSDP) for COVID-19 consists of a nasopharyngeal swab (NPS) sample processed through traditional RNA extraction (TRE) and amplified with retrotranscription quantitative polymerase chain reaction (RT-qPCR). Multiple alternatives were developed to decrease time/cost of GSDP, including alternative clinical samples, RNA extraction methods and nucleic acid amplification. Thus, we carried out a cross comparison of various alternatives methods against GSDP and each other.
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- Many labs use ELISA or CLIA tests to find anti-SARS-CoV-2 antibodies, but these methods require equipment that isn’t available in many low- and middle-income countries.
- A new dual antigen ELISA dot-blot test is introduced, offering high sensitivity and specificity to detect anti-SARS-CoV-2 IgG antibodies, and it can be done with minimal equipment in just one hour.
- This new test is also more affordable than existing rapid tests, making it a practical option for seroprevalence surveys in areas without access to advanced immunoassay facilities.