Publications by authors named "Navi Gill Dhillon"
Article Synopsis
- - Fluoride ingestion during tooth development can lead to dental fluorosis, and it activates histone acetyltransferase (HAT), which modifies the protein p53 and contributes to fluoride toxicity in specific mouse cells (LS8).
- - The study showed that fluoride modifies histone acetylation, altering gene expression in LS8 cells, as evidenced by increased acetylation levels of certain genes and corresponding mRNA expression when treated with fluoride.
- - This research is the first to highlight that fluoride treatment can lead to epigenetic changes through H3 acetylation, indicating a need for further investigation into how fluoride affects enamel development on a genetic level.
The mucus layer covering the skin of fish has several roles, including protection against pathogens and mechanical damage in which proteins play a key role. While proteins in the skin mucus layer of various common bony fish species have been explored, the proteins of shark skin mucus remain unexplored. In this pilot study, we examine the protein composition of the skin mucus in spiny dogfish sharks and chain catsharks through mass spectrometry (NanoLC-MS/MS).
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