Bispectral Index (BIS) Monitoring and Postoperative Delirium in Elderly Patients Undergoing Surgery: A Systematic Review and Meta-Analysis With Trial Sequential Analysis.

Objective: To examine the effect of bispectral index (BIS)-guided anesthesia on the incidence of postoperative delirium (POD) in elderly patients undergoing surgery.

Design: A systematic review, meta-analysis, and trial sequential analysis (TSA).

Setting: In the operating room, postoperative anesthesia care units (PACU), and ward.