Publications by authors named "Naveen T Agnihotri"
The hippocampal formation is critical for the acquisition and consolidation of memories. When recorded in freely moving animals, hippocampal pyramidal neurons fire in a location-specific manner: they are "place" cells, comprising a hippocampal representation of the animal's environment. To explore the relationship between place cells and spatial memory, we recorded from mice in several behavioral contexts.
View Article and Find Full Text PDFThe long-term stability of new hippocampal place fields requires new protein synthesis.
Proc Natl Acad Sci U S A
March 2004
Article Synopsis
- The hippocampus is essential for creating spatial memories, with specific neuron firing patterns helping in forming an internal map of the environment.
- Blocking protein synthesis in mice affects long-term stability of these spatial memories but not short-term memory or retrieval of established memory fields.
- The study shows that, similar to behavioral long-term memories, the stability of hippocampal place fields requires new protein synthesis for proper consolidation.