NIR spectroscopy-CNN-enabled chemometrics for multianalyte monitoring in microbial fermentation.

As the biopharmaceutical industry looks to implement Industry 4.0, the need for rapid and robust analytical characterization of analytes has become a pressing priority. Spectroscopic tools, like near-infrared (NIR) spectroscopy, are finding increasing use for real-time quantitative analysis.

Soft sensor based rapid detection of trace chlorine dioxide (ClO) concentration in water.

Chlorine dioxide (ClO) is a widely used sterilizer and a disinfectant across a multitude of industries. When using ClO, it is imperative to measure the ClO concentration to abide by the safety regulations. This study presents a novel, soft sensor method based on Fourier transform infrared spectroscopy (FTIR) spectroscopy for measurement of ClO concentration in different water samples varying from milli Q to wastewater.