Towards a New Era in the Management of Large Periapical Lesion in Permanent Tooth Using Stemcells: A 2-Year Clinical Application Report.

Stem cells are considered as the principal source of differentiated cells. In the past few years, the research on the stem cell in various fields had shown success, but the stem cell-based therapies in the dentistry had confined to a particular extent. The present case report was aimed to evaluate the efficacy of stem cells from human exfoliated deciduous teeth (SHED) in the management of a large periapical lesion.