Publications by authors named "Naveed-ur- Rehman Siddiqui"
Article Synopsis
- Tracheal stenosis, a complication from intubation, often gets misdiagnosed as asthma due to similar symptoms like wheezing and respiratory issues.
- A 10-year-old boy initially diagnosed with severe asthma had difficulty breathing and was unresponsive to treatment, leading to an emergency tracheostomy where tracheal stenosis was discovered.
- The case emphasizes the need for medical professionals to consider tracheal stenosis in children with respiratory symptoms, especially if there’s a history of intubation, and highlights the importance of securing the airway promptly.
Paediatric acute liver failure (PALF) is a rare yet severe condition that is associated with high mortality. Apart from liver transplant, no specific therapy exists, particularly in developing countries. Evidence suggests that removal of damage-associated molecular patterns, cytokines, toxins, and other metabolites that accumulate due to impaired liver function can enhance natural recovery.
View Article and Find Full Text PDFIntroduction: We aimed to determine the burden of respiratory disease by examining clinical profiles and associated predictors of morbidity and mortality of patients admitted to a Pediatric Intensive Care Unit (PICU) in Pakistan, a resource limited country. We also stratified the respiratory diseases as defined by the Pediatric Advanced Life Support (PALS) Classification.
Methods: A retrospective study was conducted on children aged 1 month to 18 years who were diagnosed with respiratory illness at the PICU in a tertiary hospital in Karachi, Pakistan.
Article Synopsis
- Congenital vallecular cyst is a rare cause of upper airway obstruction, with limited literature available on its incidence.
- A 10-month-old infant was initially misdiagnosed as having a foreign body due to similar symptoms, leading to an unnecessary bronchoscopy.
- After further examination in the ICU, the cyst was identified and treated, resulting in a successful extubation of the patient without further obstruction issues.
Article Synopsis
- Deep neck space infections, like retropharyngeal abscess (RPA), are rare in infants but can lead to serious complications if not diagnosed quickly.
- A 10-month-old infant presented with fever, neck swelling, hoarseness, and respiratory distress due to an RPA, requiring urgent treatment and a procedure to drain the infection.
- The case emphasizes the critical need for emergency healthcare providers to swiftly identify airway threats and manage RPAs effectively to prevent potentially life-threatening situations.
Objectives: To evaluate nationwide pediatric critical care facilities and resources in Pakistan.
Design: Cross-sectional observational study.
Setting: Accredited pediatric training facilities in Pakistan.
Objectives: Most biomarker studies of sepsis originate from high-income countries, whereas mortality risk is higher in low- and middle-income countries. The second version of the Pediatric Sepsis Biomarker Risk Model (PERSEVERE-II) has been validated in multiple North American PICUs for prognosis. Given differences in epidemiology, we assessed the performance of PERSEVERE-II in septic children from Pakistan, a low-middle income country.
View Article and Find Full Text PDFObjective: To determine the performance of a commercially available risk analytic tool (IDO2) to estimate the risk for SVO2 < 40% in patients admitted in cardiac intensive care unit (CICU).
Methods: Medical and T3 records of all patients (aged 1 day to 12 years, weight >2 kg) who received care in the CICU between October 1st, 2019 and October 1st, 2020, had SvO2 lab(s) drawn during CICU course and whose data was transmitted to T3, were included. The average IDO2 Index was computed in the 30-min period immediately prior to each SvO2 measurement and used as a predictor score for SvO2 < 40%.
Background: To determine the rate of conversion of abstracts presented at conferences into full-text articles published in peer-reviewed journals in the field of pediatric critical care medicine (PCCM) in a developing country.
Methods: We retrospectively reviewed PCCM abstracts from Pakistan presented at national and international pediatric and critical care conferences over 10 years (January 2010 to March 2020). Data included abstract characteristics, such as presentation (poster/oral), presenter (fellow/resident), time of meeting (month and year), type of meeting, study design and topic; and publication characteristics, such as journal name, time (month and year) and first author.
Background: Intracranial hypertension is not an uncommon life-threatening syndrome, caused by a variety of non-neurological and neurological illnesses, and quick diagnosis, timely treatment of Raised Intracranial Pressure (ICP) is associated with improved outcome. Our aim of study was to determine ultrasonographic measurement of Optic nerve sheath diameter (ONSD) for raised ICP.
Methods: Prospective case series done in Emergency and Paediatric critical care unit of Aga Khan University Hospital.
Objective: To assess the cost of treatment for families of children hospitalised in paediatric intensive care unit of a tertiary care teaching hospital.
Methods: The retrospective cohort study was conducted in Aga Khan University Hospital, Karachi, and comprised record of all children admitted to the paediatric intensive care unit from January 1 to June 30, 2013. Demographic data, diagnosis at the time of admission, co-morbidity, length of stay in intensive care and outcome were recorded.
Background And Aim: Advances in biomedical technology have made medical treatment to be continued beyond a point, at which it does not confer an advantage but may increase the suffering of patients. In such cases, continuation of care may not always be useful, and this has given rise to the concept of limitation of life-sustaining treatment. Our aim was to study mortality patterns over a 6-year period in a Pediatric Intensive Care Unit (PICU) in a developing country and to compare the results with published data from other countries.
View Article and Find Full Text PDFBackground: Patients in pediatric intensive care Units (PICU) are susceptible to infections with antibiotic resistant organisms which increase the morbidity, mortality and cost of care. To describe the clinical characteristics and mortality in patients with Multi-Drug Resistant (MDR) gram negative organisms. We also report safety of Polymyxin B use in these patients.
View Article and Find Full Text PDFBackground: Hypokalaemia is frequently encountered in the daily clinical practices of a paediatric cardiac intensive care unit (PCICU). It is a strong independent predictor of mortality in patients with heart failure. Thus, prompt potassium replacement therapy holds pivotal importance in therapy for hypokalaemia.
View Article and Find Full Text PDFIntroduction: Pediatric oncology patients are at increased risk of contracting healthcare-associated infections (HAIs), which are responsible for increased morbidity and mortality rates as well as treatment costs. This study aimed to identify the frequency of HAIs among pediatric oncology patients and their outcome.
Methodology: Pediatric oncology patients admitted between January 2009 and June 2010 in a pediatric ward at Aga Khan University Hospital, Karachi, Pakistan, who developed HAIs, were analyzed.