Rare homozygous cilia gene variants identified in consanguineous congenital heart disease patients.

Congenital heart defects (CHD) appear in almost one percent of live births. Asian countries have the highest birth prevalence of CHD in the world. Recessive genotypes may represent a CHD risk factor in Asian populations with a high degree of consanguineous marriages.

Tricuspid valve myxoma: An uncommon presentation of a common tumour.

Amongst the benign cardiac tumours, atrial myxomas are the commonest. Tricuspid valve attachment is an uncommon site for cardiac myxoma. Here we present the case of an 18-year-old girl who presented with a history of shortness of breath, abdominal distension, leg swelling, palpitations and dizziness for the past two months.

COVID-19 Policy Response and the Rise of the Sub-National Governments.

We examine the roles of sub-national and national governments in Canada and the United States vis-à-vis the protective public health response in the onset phase of the global coronavirus disease 2019 (COVID-19) pandemic. This period was characterized in both countries by incomplete information as well as by uncertainty regarding which level of government should be responsible for which policies. The crisis represents an opportunity to study how national and sub-national governments respond to such policy challenges.

Systolic Strain Rate In Left Ventricular Dysfunction Caused By Rheumatic Chronic Severe Mitral Regurgitation.

Background: In rheumatic severe mitral regurgitation, earlier detection of left ventricular dysfunction is very necessary in order to refer the patients for surgery at appropriate time. This study tried to find a correlation between conventional parameters of left ventricular dysfunction with systolic strain rate.

Methods: A descriptive correlational study conducted from September 2016 to March 2018.

Significance of chest pain without ST changes during exercise treadmill testing.

Background: Exercise treadmill test is interpreted as positive or negative for ischemia in the presence or absence of ST depression respectively. This study was conducted to evaluate the diagnostic value of chest pain without ST depression during exercise treadmill test.

Methods: A total of 180 patients who had abnormal exercise treadmill test result and subsequently underwent coronary angiography were studied.

Role of 64-slice multi detector computed tomography for non-invasive visualisation of coronary artery bypass grafts for follow up in post CABG patients.

Background: Coronary artery bypass graft surgery is a commonly performed revascularization procedure in ischemic heart disease patients. Conventional coronary angiography is an invasive method for evaluation of grafts in such patients. Non-invasive evaluation of grafts in post CABG patient has been made possible with the advent of 64-Slice Multi Detector Computed Tomography (MDCT) The Objective of the study was to non-invasively assess the graft patency with MDCT.

Metabolic syndrome in patients with ischemic heart disease.

Objective: To determine the frequency of metabolic syndrome in patients with Ischemic Heart Disease (IHD).

Study Design: Cross-sectional, descriptive study.

Place And Duration Of Study: Cardiology Department of Punjab Institute of Cardiology, Lahore, from June 2006 to June 2007.