Publications by authors named "Navdeep Singh"

The American Society for Pain Management Nursing (ASPMN) upholds the principle that all persons with pain have equal rights to evidence-based, high quality pain assessment, management, and treatment. This practice recommendation's goals are to 1) summarize known pain-related disparities, inequities, and injustices among commonly marginalized and at risk groups, 2) offer recommendations to ascertain that just and equitable pain care is provided to all people, and 3) outline a call to action for all nurses to embrace diversity, equity, inclusion, and a sense of belonging in order to mitigate pain-related disparities, inequities, and injustices within clinical environments and the nursing profession. This paper provides background and rationale for the 2024 ASPMN position statement on disparities, inequities and injustices in people with pain.

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Magnetic resonance imaging (MRI) provides detailed structural information of the internal body organs and soft tissue regions of a patient in clinical diagnosis for disease detection, localization, and progress monitoring. MRI scanner hardware manufacturers incorporate various post-acquisition image-processing techniques into the scanner's computer software tools for different post-processing tasks. These tools provide a final image of adequate quality and essential features for accurate clinical reporting and predictive interpretation for better treatment planning.

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A 17 year old male patient presented with bilateral preauricular sinus, right sided second branchial cleft sinus and bilateral hearing deficit. He has previous history of right congenital cataract surgery and right dacryocystorhinostomy at the age of 8 year. He was operated for branchial sinus.

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Disparities, inequities, and injustices in populations with pain are historically pervasive and lead to deleterious patient outcomes and perpetuate systemic barriers to achieving equitable pain management. The American Society for Pain Management Nursing (ASPMN) upholds the principle that all persons with pain have equal rights to evidence-based, high quality pain assessment, management, and treatment. Intervening at multilevels (i.

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Objectives: Liquid biopsy, with its noninvasive nature and ability to detect tumor-specific genetic alterations, emerges as an ideal biomarker for monitoring recurrences for locally advanced rectal cancer (LARC). Completed studies have small sample sizes and different experimental methods. To consolidate and assess the collective evidence regarding the prognostic role of circulating DNA (ctDNA) detection in LARC patients undergoing neoadjuvant chemoradiotherapy (nCRT).

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Article Synopsis
  • - Hydrophobic pollutants like long-chain hydrocarbons and heavy metals are harmful to the environment and human health, and traditional chemical surfactants used for decontamination can be toxic.
  • - Biosurfactants, produced by various microbes, are a safer and more cost-effective alternative to chemical surfactants, capable of breaking down pollutants and enhancing their solubility by reducing surface tension.
  • - The effectiveness of biosurfactants in remediation depends on several factors such as temperature, pH, and media composition, and recent discussions include their potential in a circular bioeconomy by utilizing waste for biosurfactant production.
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Background: There is limited literature describing the real-world practice of delayed initiation and shortened duration direct-acting antiviral (DAA) in kidney transplant recipients. We compared Hepatitis C virus (HCV) cure rates among kidney transplant recipients who received an HCV nucleic acid test positive (NAT +) kidney and were treated with sofosbuvir/velpatasvir (SOF/VEL) for 12 weeks or glecaprevir/pibrentasvir (G/P) for 8 weeks, a duration that is 4 weeks shorter than the guideline recommendation for treatment delay beyond 1-week post-transplant.

Methods: Retrospective study of HCV-negative adult patients who received a kidney transplant from an HCV NAT+ donor between April 2019 and April 2022 treated with either SOF/VEL for 12 weeks or G/P for 8 weeks.

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Patellar tuberculosis (TB) is a rare manifestation of musculoskeletal tuberculosis, accounting for a small proportion of cases. This case report presents a detailed analysis of a female patient in her early 30s who presented with isolated TB of the patella without concurrent pulmonary involvement. The patient received antitubercular chemotherapy, consisting of a 4-month intensive phase followed by an 8-month continuation phase.

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Background: Donation after circulatory death (DCD) or hepatitis C virus (HCV + ) liver grafts are underused among transplant centers in the United States. The study aimed to evaluate organ utilization and outcomes of liver grafts from DCD donors with HCV infection.

Methods: National registry and local center data of all deceased donor liver transplants performed between November 2016 and December 2021 were analyzed.

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Background & Aims: The average five-year survival of metastatic renal cell carcinoma (mRCC) is 71%. However, there is significant variability in patient prognosis. Immune checkpoint inhibitors (ICIs) have been introduced into the treatment landscape of mRCC.

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Background: Bacterial blight, caused by Xanthomonas oryzae pv. oryzae (Xoo), is one of the most devastating diseases of rice leading to huge yield losses in Southeast Asia. The recessive resistance gene xa-45(t) from Oryza glaberrima IRGC102600B, mapped on rice chromosome 8, spans 80 Kb with 9 candidate genes on Nipponbare reference genome IRGSP-1.

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Article Synopsis
  • Researchers aimed to create a survival prediction model for patients with stage I Non-Small Cell Lung Cancer (NSCLC) receiving stereotactic body radiation therapy (SBRT), as no such models currently exist.
  • They collected clinical data from patients across three institutions to develop and validate this model using Cox regression and artificial neural networks.
  • The model identified two prognostic groups based on survival outcomes, showing promise for clinically stratifying SBRT patients, with recommendations for further validation.
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Coal bottom ash (CBA) which is waste and environment contaminant has been used in grinded and raw form as replacement of Portland cement (PC) and natural fine aggregates (NFA) in concrete. The combined effect of grinding period (GP) (2-10 h), grinded CBA (GCBA) (10-30%), and raw CBA (0-50%) on strength and microstructural characteristics was investigated and optimized along with its sustainability assessment. An enhancement in strength parameters with an increase in GP and replacement of PC and NFA with GCBA and CBA respectively was observed.

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Melatonin is an intracellular antioxidant of sperm membrane that protects the cells from lipid peroxidation. Yet, its role as an antioxidant on semen quality of buffalo bulls is still obscure. The present study was undertaken to assess the effect of exogenous melatonin implant (18 mg/50 kg bodyweight) on post-thaw sperm characteristics, oxidative stress, endocrinological profiles and fertility of buffalo bulls.

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The scarcity of high-quality data presents a major challenge to the prediction of material properties using machine learning (ML) models. Obtaining material property data from experiments is economically cost-prohibitive, if not impossible. In this work, we address this challenge by generating an extensive material property dataset comprising thousands of data points pertaining to the elastic properties of Fe-C alloys.

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Nanomaterials of zinc oxide (ZnO) exhibit antibacterial activities under ambient illumination that result in cell membrane permeability and disorganization, representing an important opportunity for health-related applications. However, the development of antibiofouling surfaces incorporating ZnO nanomaterials has remained limited. In this work, we fabricate superhydrophobic surfaces based on ZnO nanopillars.

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Article Synopsis
  • - Glossopharyngeal neuralgia (GPN) is a rare but debilitating facial pain condition affecting less than 1 in 100,000 people, prompting research into the effectiveness of radiofrequency ablation (RFA) as a treatment option.
  • - This systematic review analyzed 18 relevant studies from over 1,580 initial articles, finding that 80.2% of the 288 patients treated with RFA reported relief or complete resolution of their pain, with some experiencing side effects like numbness and changes in taste.
  • - Limitations of the study include the lack of comparisons between different RFA techniques and potential inconsistencies in patient data and outcomes.
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Renal diseases in dogs can be diagnosed effectively using B-mode ultrasound. Point shear wave elastography (pSWE) has demonstrated usefulness in diagnosing renal diseases in human medicine. However, its application in veterinary medicine is in its nascent stage.

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  • Doubly re-entrant pillars show better liquid repellency compared to straight or single re-entrant pillars, but their hydrodynamic behavior hasn't been well understood.
  • This study combines numerical simulations and experiments to explore how structural features of the pillars affect droplet impact and surface wettability.
  • Key dimensions like height, diameter, and overhang characteristics were modified to assess their influence on making surfaces more repellent to droplets, showing potential for optimizing these structures.
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Groundwater is one of the important sources available for drinking, agricultural, domestic, and various other purposes in the study area. Study area is having agricultural importance and is famous for Basmati rice production in the world. In order to assess water suitability for irrigation and drinking purposes, 25 sampling sites were selected and water samples were collected from handpumps, borewells and motors from May 2022 to June 2022.

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Impression making in compromised residual alveolar ridge is a regular challenge in rehabilitating patients with conventional removable complete dentures. In patients who cannot afford implant-supported dentures, specialized impression technique is a viable and justified option for fabrication of complete dentures. More often, the stability of denture in such patients becomes a deciding factor between failure and success.

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Introduction: The standard of care for patients with unresectable stage III non-small cell lung cancer (NSCLC) is chemoradiotherapy (CRT) followed by consolidation durvalumab as shown in the PACIFIC trial. The purpose of this study is to evaluate clinical outcomes and toxicities regarding the use of durvalumab in a real clinical scenario.

Methods: A single-center retrospective study was conducted on patients with a diagnosis of unresectable stage III NSCLC who underwent radical CRT followed or not by durvalumab.

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