Publications by authors named "Navarro-Trivino F"

Article Synopsis
  • A study was conducted on patients with atopic dermatitis (AD) to explore the impact of atopic comorbidities like asthma and allergic rhinitis on their treatment response.
  • Data was collected from the BIOBADATOP registry, involving 509 patients, mostly adults with severe AD, and analyzed for associations between atopic comorbidities and clinical characteristics.
  • Results indicated that patients with personal atopic comorbidities had more severe symptoms and a higher history of treatments, but no significant differences in treatment response were found after 6 and 12 months, suggesting a need for longer follow-up.
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  • The rise of glucose sensors and insulin pumps has improved diabetes management, but there's been an increase in contact dermatitis cases linked to these devices due to certain allergens.* -
  • Isobornyl acrylate (IBOA) is a major allergen found in some glucose sensors, leading to its removal from specific products, yet it still appears in many others.* -
  • The potential benefits of these diabetes devices can be overshadowed by allergic reactions, prompting dermatologists to work with endocrinologists and manufacturers to find alternative solutions for affected patients.*
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  • Patch test outcomes can be affected by age, but there are mixed findings on how age impacts these results.
  • The study involved over 13,000 patients and revealed that middle-aged adults (31-65 years) had the highest rates of positive skin sensitisation results, particularly for certain substances like nickel and potassium dichromate.
  • Overall, while age does influence some patch test results, most allergens showed consistent reactivity across ages, underscoring the importance of standard testing regardless of age.
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  • Head and neck dermatitis (HND) is a severe form of atopic dermatitis that primarily affects seborrheic areas and significantly impacts patients’ quality of life, with treatment being complicated by the ineffectiveness of usual topical therapies and the potential for dupilumab-associated dermatitis (DAHND).
  • Research indicates that fungi, particularly Malassezia species, play a crucial role in HND development, as they activate the immune system and cause inflammation via specific immune pathways.
  • While antifungals show promise in treating HND, particularly in oral form, the long-term effects are uncertain; new therapies like Janus kinase inhibitors and OX40 inhibitors are being explored, and factors like host microbiome variations could lead to more
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Background: Budesonide and tixocortol pivalate as markers of contact allergy to corticosteroids have been questioned, as they are not able to detect a significant percentage of allergic patients.

Objectives: To investigate the potential role of clobetasol propionate in enhancing corticosteroid sensitisation detection.

Methods: Between January 2022 and December 2023, patients who attended centres involved in the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy were tested with an extended baseline series that included budesonide, tixocortol pivalate, clobetasol propionate 0.

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After the meeting held by the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC) back in October 2021, changes were suggested to the Spanish Standard Series patch testing. Hydroxyethyl methacrylate (2% pet.), textile dye mixt (6.

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Allergic contact dermatitis induced by the use of ophthalmic topical drugs is one of the most common causes of eyelid dermatitis. The introduction of new formulations, both of active ingredients and excipients, and the lack of marketing in some of them, makes patch testing in patients whose source of contact are topical ophthalmic drugs truly challenging. Across this manuscript, most, if not all, topical ophthalmic drugs used in our national health system have been collected, including information on the allergens available, and the concentration and vehicle advised for those that still remain unavailable.

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Background/objectives: The evaluation of the efficacy and safety of new molecules for atopic dermatitis (AD) in real clinical practice is very important to obtain information that clinical trials (EECC) lack. The pattern of AD in the head and neck (H&N) continues to be a challenge in treatment today, despite the new molecules, and real-life data on the use of tralokinumab is still missing. This is the first daily practice study of tralokinumab treatment in patients with H&N AD pattern.

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Article Synopsis
  • Facial edema is a common issue in patients visiting allergology and dermatology clinics, but diagnosing its cause can be difficult for doctors.
  • Facial angioedema has multiple underlying causes, such as histaminergic and bradykinergic responses, which need to be differentiated from other conditions like infections and autoimmune diseases.
  • A thorough diagnostic strategy is crucial for conducting the right tests and administering effective treatment for facial edema-related conditions.
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The development and commercialization of glucose sensors and insulin pumps has revolutionized the management of diabetes. These devices have been linked to multiple cases of contact dermatitis in recent years, however, giving rise to a growing interest in identifying the sensitizing allergens. Isobornyl acrylate was clearly identified as one of the main allergens responsible for contact dermatitis among users of the FreeStyle glucose sensor and was subsequently removed from the product ingredients.

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Hand-foot eczema (HFE) are special locations of dermatitis, which are often associated with atopic dermatitis (AD) and have a significant negative impact on the quality of life, demanding a clinically relevant improvement. To evaluate the effectiveness and safety of dupilumab in the treatment of eczema localized in hands and/or feet in patients with moderate-to-severe AD. Retrospective multicenter study of adult patients with HFE treated with dupilumab for their AD.

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