Publications by authors named "Nava Mehdiani"
Premature birth is a traumatic event that puts mother and child at risk for subsequent psychopathology. Skin-to-skin contact in the form of intermittent kangaroo mother care has been shown to positively affect the infant's stress response and cognitive development, but underlying mechanisms remain unclear. Moreover, first skin-to-skin contact is usually delayed for days after birth.
View Article and Find Full Text PDFThis study was performed to identify transcriptional alterations in male intrauterine growth restricted (IUGR) rats during and at the end of nephrogenesis in order to generate hypotheses which molecular mechanisms contribute to adverse kidney programming. IUGR was induced by low protein (LP) diet throughout pregnancy, bilateral uterine vessel ligation (LIG), or intrauterine stress (IUS) by sham operation. Offspring of unimpaired dams served as controls.
View Article and Find Full Text PDFArticle Synopsis
- Increasing knowledge about rare diseases has led to the development of new treatments targeting specific genetic issues and biological pathways associated with these conditions.
- Several drugs have been approved, such as asfotase alfa and burosumab, while others are in advanced clinical trials, indicating a promising future for therapy in these areas.
- It is recommended that patients receive care at specialized centers to ensure safety and to allow for data collection that can improve treatment strategies, which could also inform family decisions during pregnancy regarding skeletal diseases.