Mesodorylaimus ushkaniensis sp. n. and Allodorylaimus baikalensis sp. n. (Nematoda, Dorylaimida) from Lake Baikal, Russia.

Two new nematode species of the order Dorylaimida from Lake Baikal sediments are described and illustrated. Mesodorylaimus ushkaniensis sp. n.

[Risk factors for obstructive sleep apnea in socio-demographic groups of the population of Chuvashia].

Objective: To study risk factors (RF) of obstructive sleep apnea syndrome (OSAS) in the socio-demographic groups of the population of Chuvashia.

Materials And Methods: An anonymous survey included 2161 residents of Chuvashia (1007 men, 1154 women), aged from 18 to 70 years, average 36.5±13.

Review of the free-living Nematode (Nematoda) fauna of Lake Baikal.

A complete list of free-living nematodes found in Lake Baikal is presented. A total of 112 species of roundworms from 32 genera, 16 families and 8 orders are listed. The locations and depths of nematode finds in Baikal are indicated, information on their distribution is summarized, and zoogeographical characteristics for each species are given.

Prodorylaimus baikalensis sp. n. and Mononchus minutus sp. n. (Nematoda) from Lake Baikal, Russia.

Two new nematode species found in Lake Baikal (Russia) are described and illustrated. Prodorylaimus baikalensis sp. n.

sp. n. and sp. n. (Nematoda, Triplonchida) from Lake Baikal, Russia.

Two new nematode species found in Lake Baikal (Russia) are described and illustrated. Tobrilus saprophagus sp. n.

sp. n. and sp. n. (Nematoda, Triplonchida) from Lake Baikal, Russia.

Two new nematode species found in Lake Baikal (Russia) are described and illustrated. Tobrilus methanus sp. n.

Ethmolaimus riparius sp. n. and Paramononchus major sp. n. (Nematoda) from Lake Baikal, Russia.

Two new nematode species found in Lake Baikal (Russia) are described and illustrated. Ethmolaimus riparius sp. n.

[Serum markers of fibrosis and endothelial dysfunction in patients with alcoholism, with varying degrees of liver fibrosis].

In the serum of patients with alcoholism with varying degrees of severity of liver fibrosis were studied the content markers of fibrosis, endothelial dysfunction and proinflammatory cytokines. Concentration in blood indicators of fibrogenesis--collagen type 4, hyaluronic acid, TIMP-1, TIMP-2, YKL-40 and MMP-2 is considerably increased at the 4 degree of fibrosis and moderately increased at low and zero degrees of liver fibrosis. Similar results were obtained in respect of proinflammatory cytokines Il-6, IL-8, IL-12/p70 and IL-12/p40.

[The role of lipoprotein-associated enzyme paraoxonase 1 and its polymorphisms in the pathogenesis of endothelial dysfunction and somatic complications in patients with alcoholism: Review ].

A review of recent data on the role of the multifunctional enzyme, associated with high density lipoproteins - paraoxonase 1 (PON1) in maintaining healthy endothelial function by detoxifying both oxidized low density lipoproteins and homocysteine thiolactone. The additional contribution to the protection of the endothelium against damage makes organophosphatase activity of PON1 involved in the detoxification products of tobacco smoke. The reduction of antioxidant activity of PON1 promotes the differentiation of monocytes into macrophages and the development of inflammation.

[Blood Content of Markers of Inflammation and Cytokines in Patients With Alcoholic Cardiomyopathy and Ischemic Heart Disease at Various Stages of Heart Failure].

We conducted a comparative study of content proinflammatory cytokines, biomarkers of inflammatory process, biochemical indicators of congestive heart failure (CHF) and hemodynamic parameters in patients with alcoholic cardiomyopathy (ACMP) and ischemic heart disease (IHD) with various NYHA classes. We examined 62 men with ACMP (n = 45) and IHD (n = 17) and NYHA class III-IV CHF. Patients of both groups had lowered ejection fraction (EF), dilated cardiac chambers, and increased left ventricular (LV) myocardial mass index (MMI).

[Blood Content of Markers of Inflammation and Cytokines in Patients With Alcoholic Cardiomyopathy and Ischemic Heart Disease at Various Stages of Heart Failure].

We conducted a comparative study of content proinflammatory cytokines, biomarkers of inflammatory process, biochemical indicators of congestive heart failure (CHF) and hemodynamic parameters in patients with alcoholic cardiomyopathy (ACMP) and ischemic heart disease (IHD) with various NYHA classes. We examined 62 men with ACMP (n=45) and IHD (n=17) and NYHA class III-IV CHF. Patients of both groups had lowered ejection fraction (EF), dilated cardiac chambers, and increased left ventricular (LV) myocardial mass index (MMI).

[Mechanisms of the liver anti-endotoxin defence].

Current knowledge of immunocellular and lipoprotein mechanisms of the liver-induced anti-endotoxin tolerance has been summarized. The role of T regulatory cells, different macrophage phenotypes, high density lipoproteins, oxidized low density lipoproteins and their receptors as the key players in mechanism of tolerance to endotoxin has been discussed.

Apospory appears to accelerate onset of meiosis and sexual embryo sac formation in sorghum ovules.

Background: Genetically unreduced (2n) embryo sacs (ES) form in ovules of gametophytic apomicts, the 2n eggs of which develop into embryos parthenogenetically. In many apomicts, 2n ES form precociously during ovule development. Whether meiosis and sexual ES formation also occur precociously in facultative apomicts (capable of apomictic and sexual reproduction) has not been studied.

[Apomixis and amphimixis in flowering plants].

The light microscopic and ultrastuctural events of apomictic seed development from the earliest stages through the embryo and endosperm development to maturity were compared with those of the sexual one. The problem of autonomous endosperm formation was postulated as the main problem in low apomictic seed set. The characteristic features of fine differentiation of megasporocytes at diplospory, aposporous initials at apospory, embryocytes at adventive embryony as well as the egg cells at parthenogenesis and synergids at apogamety were described and compared with sexual reproductive structures.

[The course of Helicobacter pylori-associated duodenal ulcer concurrent with chronic opisthorchiasis].

The purpose of the investigation was to study the specific features and the course of Helicobacter pylori-associated duodenal ulcer (DU) concurrent with chronic opisthorchiasis (CO) A hundred and twenty-seven patients with H. pylori-associated DU were examined. Of them 78 patients were found to have H.

[DNA-abzymes in rheumatoid arthritis: pathogenetic and clinical significance].

Aim: To study possible pathogenetic role and clinical significance of DNA-hydrolysing autoantibodies (autoAB) or DNA-abzymes in patients with rheumatoid arthritis.

Material And Methods: Prevalence of DNA-abzymes and their catalytic activity were studied in 400 patients with rheumatoid arthritis (RA) and 88 healthy donors matched by age and gender.

Results: Associated with DNA-binding autoAB DNA-hydrolysing activity was detected in 41.

[Achievements and prospects of clinical abzymology].

Catalytic autoantibodies (abzymes) are autoantibodies that are potentially ready to realize certain effects in the organism, first of all antibody-mediated catalysis and cytotoxicity. Natural abzymes with protolytic (protabzymes) and DNA-hydrolyzing DNA-abzymes) activity are of the greatest interest. The most impressive example of the catalytic activity of protabzymes is hydrolysis of specific proteins, revealed in patients with autoimmune diseases, such as bronchial asthma (vasoactive intestinal neuropeptide), autoimmune thyroiditis (thyroglobulin), multiple sclerosis (myelin basic protein), and autoimmune myocarditis (cardiomyosin).

[Disorders in the immune status and hepatic pathologies in young heroin addicts].

The immunocytograms of 166 patients with opiomania, primarily of the heroin variation, aged 15 to 19, were examined. 18 healthy teenagers of the same age were in the control group. The sampling comprised both patients without any signs of infectious diseases (86 persons) and patients with viral hepatitis B and C.

[Responses of Seidlitzia rosmarinus to salt stress].

The responses of the salt-accumulating halophyte Seidlitzia rosmarinus to salt stress (500 mM NaCI) were studied. Observations were carried out over the span of 72 h. Three phases of responses were identified.