Publications by authors named "Naufal N Firsty"

Prostate enlargement known as benign prostatic hyperplasia (BPH) increases the risk of infection in the urinary tract by obstructing or blocking the prostatic portion of the urethra. This disease becomes more common as people age.

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  • The study investigates how prior lupus nephritis (LN) affects kidney transplantation (KTx) outcomes in patients with end-stage kidney disease (ESKD), comparing them to those with ESKD due to other causes.
  • A meta-analysis of 10 studies involving 1,299 KTx revealed similar graft and recipient survival rates for both LN and non-LN patients at various follow-up points, indicating no significant difference.
  • The results suggest that lupus nephritis has a negligible impact on the prognosis of kidney transplantation outcomes for ESKD patients when compared to other underlying causes.
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Background: Breast cancer (BC) remains a significant global concern, particularly among developing countries in South-East Asia (SEA) and South America (SA). The socioeconomic burdens of oncologic care in those countries were often originated from limited accessibility on attainable therapeutic options and reliability on identifying essential information of cancer cells, i.e.

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Background: Non-small cell lung cancer (NSCLC) stands as one of the most prevalent types of cancer worldwide, driving extensive research in oncologic therapeutic approaches. Atezolizumab, among the treatments under scrutiny, is undergoing evaluation as a potential first-line therapy for NSCLC. This review aims to assess the efficacy of atezolizumab in treating patients with NSCLC and to shed light on the ongoing quest for the most effective treatment.

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  • - The study investigates the effectiveness and safety of olaparib, a PARP inhibitor, in treating metastatic castration-resistant prostate cancer (mCRPC), showing positive treatment outcomes and acceptable safety profiles compared to existing guidelines.
  • - A meta-analysis of three clinical trials with 1,325 mCRPC patients showed that adding olaparib significantly improved progression-free survival (PFS) and overall survival (OS), especially in patients with specific gene mutations such as HRR and ATM.
  • - Despite the promising results, the olaparib group experienced a higher rate of adverse effects, prompting the need for further research to better understand its overall efficacy and safety in this patient population.
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Background: To date, early cancer detection is considered vital to reduce the global cancer burden through low-cost, but accurate screening modalities. The anatomical positioning of prostate cancer (PCa) created a potentially distinctive diagnostic method through the identification of volatile organic compounds (VOCs) in urine, which might be detectable not by humans but by canine species. This review aimed to capture the potential of the medical detection canine (MDC) to detect PCa by providing its diagnostic accuracy estimation on urine odor testing.

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Background: The interplay between platelet and breast cancer (BC) pathology may have the potential to represent the malignancy status itself, evidently through predicting the histopathological results of each individual. This study aims to elaborate on the diagnostic value of a higher platelet count or thrombocytosis and the histopathological status of invasive BC in our center, explaining its correlation from the diagnostic perspective.

Materials And Methods: A retrospective cohort study was conducted using breast cancer patients' medical records from January to March 2022 at the Haji Adam Malik General Hospital, Medan, Indonesia.

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  • - Cat scratch disease (CSD) is an infectious illness from a cat's scratch or bite, which can lead to symptoms similar to lymphoma, making diagnosis tricky.
  • - A 24-year-old Indonesian male initially suspected to have lymphoma was diagnosed with CSD after presenting with painful masses in his arm and armpit, as well as a recent cat bite.
  • - Proper diagnostic measures like imaging and biopsy are crucial to avoid misdiagnosis and ensure effective treatment, as demonstrated by the patient's successful recovery following appropriate care.
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Background: The identification of the novel targeted therapy i.e., cyclin-dependent kinases (CDKs) 4/6 inhibitor as combined with the endocrine regimen revealed a considerable capability to increase the managements' effectivity of hormone-receptor-positive (HR+) and HER2- breast cancer (BC).

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Background: Axillary lymph node (ALN) involvement in breast cancer (BC) is considered to be a significant factor in determining the diseases' extent at the moment. The spreading capacity of cancerous cells may linearly correlate with its activity level, which in turn alter the coagulation function as commonly represented by fibrin degradation biomarker i.e.

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Propolis is a resinous beehive product that has a wide range of biological activities, namely antimicrobial, antioxidant, and anti-inflammatory properties. Propolis is collected by the bees from plant resin and exudates to protect hives and maintain hive homeostasis. The aim of the present systematic scoping review is to explore the potential and suitability of propolis as an adjunctive treatment in breast cancers, based on the latest available experimental evidence (2012-2021).

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