Bone-mimicking scaffolds based on silk fibroin (SF) mixed with hydroxyapatite nanoparticles (HA NPs) and titanium oxide (TiO) nanoparticles were created as materials for bone formation. Six scaffold groups were fabricated: S1 (SF), S2 (Silk + (HA: TiO; 100: 0)), S3 (Silk, (HA: TiO; 70: 30)), S4 (Silk + (HA NPs: TiO; 50: 50)), S5 (Silk + (HA: TiO; 30: 70)), and S6 (Silk + (HA NPs: TiO; 0:100)). Scaffolds were characterized for molecular formation, structure, and morphology by Fourier transform infrared spectroscopy, element analysis, and X-ray diffraction.
View Article and Find Full Text PDFMembranes which have an osseointegration abilty are often selected as biomaterials in oral and maxillofacial surgery. Although these membranes are often the best option for certain uses, it is a challenge to create functionally attractive membranes. In this research, electro-spun titanium oxide (TiO2)/hydroxyapatite (HA)/polyurethane (PU) membranes were fabricated with different ratios of HA and TiO2: 100: 0, 70:30, 50:50, 30:70 and 0:100 w/w.
View Article and Find Full Text PDFGuided bone regeneration is an effective method that can enhance bone volume at a defect site of the mandible before material implantation. Layer-by-layer electrospun membranes of polyurethane/silk fibroin (SF) were fabricated to mimic oral soft tissue. The electrospun polyurethane fibers were initially fabricated into a membrane.
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