Publications by authors named "Natsumi Nakaoka"

Article Synopsis
  • Microbubbles can be used to deliver drugs and genes, with their release being triggered by ultrasound applied inside blood vessels.
  • Research shows that when a microbubble with a DMPC shell is exposed to pulsed ultrasound, the amount of DMPC molecules that detach reaches up to 70%.
  • The study also indicates that the intensity of the bubble's vibrations correlates with the rate of molecular desorption, suggesting that ultrasound can effectively control this process.
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In the pharmaceutical field, a technique to level the surface of powdered medicines is important in the dispensing process because the flatness of the powder surface affects the packaging accuracy directly. This paper investigates a method for leveling of the surface profile of powder using ultrasound vibration on a plate. The system used comprises a V-shaped plate and two ultrasound transducers, and the plate configuration required was determined from the results of simulations performed by finite element analysis.

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