Publications by authors named "Natsumi Maru"

Article Synopsis
  • Perioperative acute ischemic stroke is a rare but serious complication in patients undergoing lung resection, particularly in those having left upper lung lobectomies for lung cancer.
  • In this case, a 67-year-old man developed sudden left side weakness and difficulty speaking two days after surgery due to a large thrombus blocking his carotid arteries.
  • The blockage was treated successfully with endovascular stenting, leading to significant recovery, and the patient was discharged home after 19 days.
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Purpose: There is limited evidence concerning the computed tomography (CT) follow-up interval to detect recurrence and second primary cancers after surgery for non-small-cell lung cancer (NSCLC). In this study, we aimed to investigate the impact of CT interval on survival after surgery.

Methods: This retrospective study analyzed the prognosis of 103 patients who underwent periodic CT after complete resection for pathological stage II-III NSCLC at a single institute between 2015 and 2020.

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Purpose: Patients with part-solid adenocarcinomas treated by surgery generally have more favorable outcomes than those with pure-solid adenocarcinomas. We conducted this study to understand the effects of the lepidic components and preoperative characteristics on the postoperative survival of patients with part-solid adenocarcinomas.

Methods: The subjects of this retrospective study were 313 patients with stage 1 part-solid adenocarcinomas and 634 patients with pure-solid adenocarcinomas, treated at our institution between 2006 and 2020.

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Objectives: Postoperative air leakage is a major complication of lung resection, particularly right upper lobectomy. However, various surgical procedures can reduce postoperative complications and shorten the drainage period. The current study aimed to analyse the utility of bronchus-first right upper lobectomy as an alternative routine procedure.

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Background: Pulmonary abscess is a severe infection commonly seen in patients with chronic obstructive pulmonary disease, interstitial pneumonia, immune deficiency disease, drug-induced immunocompromised state, and congenital pulmonary disease. The treatment strategy in pregnant women with a pulmonary abscess is considered challenging since adverse effects on the fetus must be avoided to ensure safe delivery.

Case Presentation: A 34-year-old female patient at 24 weeks of gestation (G2P1) was admitted to the Department of Obstetrics and Gynecology due to sudden right chest pain.

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Article Synopsis
  • Alveolar adenoma is a rare and benign lung tumor that often appears as a solitary cystic nodule, making it hard to differentiate from other lung tumors based on imaging alone.
  • Diagnosis relies on histopathological and immunohistochemical analyses, as seen in a case study of a 50-year-old male patient who presented with chest pain and was ultimately found to have this condition after surgery.
  • Post-surgery, the patient showed no signs of malignancy or recurrence after 46 months, highlighting the generally favorable prognosis for those diagnosed with alveolar adenoma.
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An 80-year-old man with surgical history of colon cancer was referred to our department for surgical treatment for multiple metastatic lung tumors in the left upper lobe. The patient had been showing complete atelectasis of the left lower lung lobe one year prior to the consultation. Six months after wedge resections for the pulmonary metastases, the left lower lobe was re-expanded, showing bronchiectasis with rudimentary pulmonary artery branches.

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A female patient in her 40s who underwent surgery for recurrent right lung metastasis from resected ovarian cancer was referred to our department because of the right pneumothorax due to radiofrequency ablation for multiple lung metastases. Methicillin-resistant Staphylococcus epidermidis( MRSE) was detected from the tip of the drainage catheter indicated persistent pulmonary fistula with right empyema, and surgical treatment was performed. A white coat of the whole lung surface and air leakage were observed at radiofrequency ablation (RFA) treated lesion and partial resection of the right lung, debridement, and irrigation were performed.

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Background: Postoperative cerebral infarction is a rare but serious complication after lung cancer surgery. We aimed to investigate the risk factors and evaluate the efficiency of our devised surgical procedure to prevent cerebral infarction.

Methods: We retrospectively examined 1,189 patients who underwent a single lobectomy for lung cancer at our institution.

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Article Synopsis
  • A 46-year-old man experienced sudden difficulty breathing and was diagnosed with a right-sided tension pneumothorax after a chest X-ray.
  • He was transferred to a different hospital for further treatment since the initial chest drainage was ineffective.
  • After a chest CT scan revealed giant bullae in the right lung, he underwent surgery, which resulted in improved respiratory function post-operation.
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Purpose: The surgical Apgar score (SAS)-calculated using the intraoperative variables estimated blood loss, lowest heart rate, and lowest mean systolic pressure-is associated with mortality in cancer surgery. We investigated the utility of the SAS in patients with lung cancer undergoing surgery.

Methods: We retrospectively analyzed the data of 691 patients who underwent surgery for primary lung cancer between 2015 and 2019 in a single institute and analyzed the impact of the SAS.

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Article Synopsis
  • * Analysis revealed that symptom severity, particularly pain, exhibited a rebound effect starting around day 3 or 4, with significant differences in pain levels between those who recovered and those who did not.
  • * Pain severity on day 4 was found to be a strong predictor for early recovery, while the duration of symptoms contributed most to postoperative distress.
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Objectives: The surgical Apgar score, calculated using 3 intraoperative variables (blood loss, lowest mean arterial pressure and lowest heart rate), is associated with mortality in cancer surgery. The original score has less applicability in lung cancer surgery; therefore, we innovated the modified pulmonary surgical Apgar score with additional intraoperative oxygen saturation representing pulmonary parenchymal damage and cardiopulmonary dynamics.

Methods: We retrospectively analysed the data of 691 patients who underwent surgery for primary lung cancer between 2015 and 2019 at a single institute.

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Objectives: This study aimed to elucidate the outcomes of emergency salvage surgery following life-threatening events (serious haemorrhage and/or infections) among patients with lung cancer who had undergone chemo- and/or radiotherapy.

Materials And Methods: We analysed the data of patient from 2015 to 2020, retrospectively. The clinical characteristics, including preoperative treatment, perioperative outcomes and survival time, were analysed.

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Background: Meningioma is the most common type of benign primary brain tumor that is rarely associated with distant metastasis. No established treatment strategy for metastatic meningiomas exists to date. Herein, we report a case of solitary pulmonary metastasis of meningioma detected 2 years after neurosurgical resection of the primary tumor.

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A 70-year-old woman underwent right S6 segmentectomy and left S6 partial resection for lung metastasis of uterine cervix cancer. Although she received adjuvant chemotherapy, chest computed tomography revealed a new pulmonary nodule on the staple stump of the right lung. We diagnosed the tumor as local recurrence at the stump and planned to continue chemotherapy.

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Article Synopsis
  • Hypercalcemia, often seen in cancer, is typically linked to parathyroid hormone activation but can also be caused by other factors, as shown in a specific case.
  • A 76-year-old man experienced hypercalcemia due to excessive production of 1,25-dihydroxyvitamin D resulting from a high-grade fetal lung adenocarcinoma, with the tumor and surrounding cells showing a key enzyme related to this overproduction.
  • After surgically removing the lung tumor, the patient's calcium levels returned to normal, indicating that the cancer-induced 1,25-dihydroxyvitamin D overproduction was the main cause of his hypercalcemia rather than the usual PTH-related mechanisms.
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A 62-year-old male patient underwent median sternotomy and thymectomy for thymoma (World Health Organization classification type B1+B3, Masaoka classification stage II). A 10-month follow-up postoperative computed tomography showed a 22-mm nodule in the anterior mediastinal lipid tissue just above the right diaphragm. The patient was followed for 8 years, and the nodule's capsule eventually became calcified.

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Background: Salvage surgery is an effective therapeutic option for patients experiencing relapses after chemoradiotherapy for advanced-stage lung cancer or after high-dose radiotherapy for early-stage lung cancer. We report a case involving an emergent salvage surgery for a patient with massive hemoptysis who developed lung cancer recurrence after undergoing proton beam therapy 7 years prior to presentation.

Case Presentation: A 70-year-old male patient was emergently admitted due to massive hemoptysis.

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Red cell distribution width (RDW) is a prognostic factor for various malignancies, including colorectal, breast and lung cancer. The effect of preoperative RDW on the prognosis of patients who have undergone surgery for non-small cell lung cancer (NSCLC) was investigated in the present study. This retrospective, single-institution study included consecutive patients who had undergone complete NSCLC resection between January 2006 and December 2013 at the Department of Thoracic Surgery of Kansai Medical University Hospital (Hirakata, Japan).

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Background: Immunoglobulin G4-related disease (IgG4-RD) is a multi-organ disorder predominantly occurring in middle-aged to elderly male patients characterized by multi-organ fibrosis, specific pathological findings of storiform fibrosis with IgG4-positive plasma cell infiltration, and elevated serum IgG4 level. We herein report a rare presentation of IgG4-RD forming an isolated mass in the middle mediastinum mimicking a mediastinal tumor and discuss the clinical significance of mediastinal IgG4-RD.

Case Presentation: An 82-year-old male patient without any symptom was referred due to left middle mediastinal mass (3.

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Objective: The surgical result of early-staged lung cancer is not satisfactory due to unexpected postoperative lymph node metastasis and recurrence. This study aimed to investigate which preoperative factors-including the standard uptake value max (SUV) of positron emission tomography-could predict occult lymph node metastasis and survival.

Methods: We retrospectively analyzed data from 598 patients with clinical stage I lung cancer who underwent surgery, and examined their preoperative clinical characteristics.

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Pulmonary benign metastasizing leiomyoma (PBML) is a rare entity. We herein report a case of PBML found as multiple bilateral lung nodules 11 years after total hysterectomy. The patient was a 53-year-old woman with past surgical history of abdominal total hysterectomy for a uterine leiomyoma at the age of 42.

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Background: Anomalous systemic arterial supply to the basal segment of the lung (ABLL) is a relatively rare congenital anomaly characterized by aberrant systemic arterial blood flow to the basal segment of the lung. We experienced a rare presentation of ABLL, in which a giant aberrant artery with the same dimensions as that of the descending aorta flowed from the celiac artery to left lower lobe.

Case Presentation: An otherwise healthy 42-year-old man was referred to our department due to an abnormal chest X-ray.

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