Publications by authors named "Natsumi Katsumata"
The concentration of the radioactive cesium (134Cs and 137Cs) in soils and in atmospheric fallouts has been measured at the Koriyama campus, Nihon University, after the Fukushima Dai-ichi Nuclear Power Plant accident for 13 y, from October 2011 till September 2023 and now ongoing. The concentration of them decreased very rapidly due to decontamination activities and weathering effects, with an environmental half-life of 1.21 and 2.
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- Dialysis patients face a heightened risk of developing renal cell carcinoma (RCC), but distinguishing RCC from benign cysts can be challenging with standard imaging techniques like CT and ultrasound.
- This study conducted between 2012 and 2016 used FDG-PET/CT to screen for RCC in 150 participants with end-stage renal disease, with evaluations made by three radiologists.
- The results showed that FDG-PET/CT had a high sensitivity (100%) and negative predictive value (100%), ultimately diagnosing RCC in seven out of twenty patients identified as positive for malignancy.
Introduction: This study aimed to assess the utility of quantitative high-resolution computed tomography (HRCT) for determining the clinical course of anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis-associated interstitial lung disease (MDA5 ILD).
Method: This study retrospectively analyzed the data of 34 patients with MDA5 ILD to determine the association between the clinical findings and extent of ILD via quantitative CT analysis at baseline and short-term follow-up. Quantified HRCT scores were evaluated as the lung severity score (LSS), percentage of opacity, and percentage of high opacity.
Article Synopsis
- - This study explores a method called pretargeting radioimmunotherapy (PRIT) to treat triple-negative breast cancer (TNBC), aiming to decrease harmful blood radioactivity and associated side effects.
- - The researchers optimized a three-step PRIT approach using biotinylated antibodies and radiolabeled proteins, demonstrating that the right doses and modifications can significantly reduce kidney radioactivity while maintaining effectiveness against tumors.
- - Results showed that this optimized PRIT approach led to reduced tumor growth in treated mice compared to untreated controls, suggesting potential effectiveness for future human TNBC treatments.
The overexpression of vascular endothelial growth factor (VEGF) in varying types of solid tumor renders radioimmunotherapy (RIT) with the anti-VEGF antibody bevacizumab (BV) a promising treatment. However, the slow blood clearance of BV, which may increase the occurrence risk of hematotoxicity, hinders the application of BV-RIT. Using the avidin chase is a long-known blood clearance enhancement strategy for biotinylated-mAb.
View Article and Find Full Text PDFPurpose: The objective of this study was to characterize cervical computed tomography (CT) findings in Kawasaki disease (KD) patients that may facilitate early diagnosis.
Methods: We retrospectively reviewed cervical CT images of 78 children with cervical lymphadenopathy to analyze the distribution and morphology of lymphadenopathy and other soft-tissue findings.
Results: Twenty-eight patients were diagnosed with KD.