Publications by authors named "Natsume Fujitate"
Article Synopsis
- Patients with hemophilia A who have inhibitors often show unresponsiveness to repeated doses of recombinant factor VIIa (rFVIIa), likely due to lower levels of factor X (FX) in their blood.*
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- A study involving both hemophilia patients with inhibitors and those with acquired hemophilia found that unresponsive patients had significantly lower FX levels, which affected their thrombin generation and response to rFVIIa treatment.*
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- The presence of emicizumab, a prophylactic treatment, improved thrombin generation even at low FX levels, suggesting it may enhance coagulation despite reduced clinical effectiveness of rFVIIa in these patients.*
