Publications by authors named "Natsuko Yoshimi"
Article Synopsis
- - Whole exome sequencing (WES) is increasingly used to identify genetic causes of inherited disorders in humans and has been applied to dog genetics as well.
- - The study focused on neuroaxonal dystrophy (NAD) in Papillon dogs, identifying 10 candidate mutations by sequencing affected and unaffected dogs, of which one mutation (PLA2G6 c.1579G>A) was linked to the disease.
- - The findings suggest that this mutation not only contributes to NAD in dogs but also aligns with a known human gene associated with a similar disease, highlighting WES's effectiveness for studying rare hereditary conditions in canines.
We investigated the epidemiological characteristics of intervertebral disc herniation (IVDH) in Japan in a large population using a retrospective study. The sample population was dogs (n=297) with IVDH in Japan. Medical records were reviewed for breed, sex, age, affected interspace and neurological severity.
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