Publications by authors named "Natsuki Aoki"
Objective: The present study aimed to observe and analyze the ocular movements induced by Coriolis stimulation (eccentric pitch while rotating: PWR) that induces Coriolis forces on the vestibular apparatus of healthy human individuals.
Methods: A total of 31 healthy subjects participated in the study. Eccentric PWR was performed on 27 subjects, by pitching the participants' heads forward and backward at an angle of 30° each on an axis parallel and 7 cm below inter-aural axis, at a frequency of 0.
Background: Vestibular stimulation causes postural unsteadiness accompanied by a sensation of tilt.
Aims/objectives: The mechanism of the sensation of tilt needs to be assessed by accurate calculation of the rotational axis of torsional eye position under various vestibular stimulations.
Material And Methods: Twenty-two healthy subjects participated in the study.
Patients with SLC26A4 mutations exhibit highly variable hearing loss and vestibular dysfunction. Although Slc26a4 mutant mice similarly exhibit vestibular deficits, including circling behavior, head tilting, and torticollis, the underlying pathogenesis of the vestibular symptoms remains unclear, hindering its effective management for patients with SLC26A4 mutations. In this study, we evaluated the equilibrium function using the inspection equipment, which can record eye movements against rotational, gravitational, and thermal stimulations.
View Article and Find Full Text PDFCholesteatoma has an altered microbiota with a higher abundance of species.
Laryngoscope Investig Otolaryngol
December 2022
Article Synopsis
- - The study aimed to compare the microbiota of cholesteatomas and chronic suppurative otitis media (COM) to identify potential pathogens linked to cholesteatoma phenotypes.
- - Analysis of surgical specimens showed significant differences in bacterial composition between cholesteatomas and COM, with certain bacteria being more prevalent in cholesteatomas.
- - Findings indicate that coagulase-negative staphylococci (CoNS) could serve as biomarkers for cholesteatomas, and their abundance was positively correlated with the size of the cholesteatoma, suggesting their role in disease progression.
Enhanced fallopian canal as a potential marker for temporal bone vasculitis.
Laryngoscope Investig Otolaryngol
December 2020
Objectives: This study aimed to test the hypothesis that contrast-enhanced 3D MRI with gradient-echo sequences (CE-3D-GRE) can detect signs of vasculitis in the fallopian canal, which may cause otologic involvement, in four patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV).
Methods: CE-3D-GRE acquired at 3.0 Tesla was performed on four patients diagnosed with granulomatosis with polyangiitis or eosinophilic granulomatosis with polyangiitis, at onset or relapse of the disease, and in remission.