Comparison of pharmacokinetic variables for creatinine and iohexol in dogs with various degrees of renal function.

Objective: To compare pharmacokinetics and clearances of creatinine and iohexol as estimates of glomerular filtration rate (GFR) in dogs with various degrees of renal function.

Animals: 50 Great Anglo-Francais Tricolor Hounds with various degrees of renal function.

Procedures: Boluses of iohexol (40 mg/kg) and creatinine (647 mg/kg) were injected IV.

MRI findings of a middle ear cholesteatoma in a dog.

This article describes the MRI features of a middle ear cholesteatoma in an 8 yr old flat-coated retriever. Physical examination revealed pain on opening the jaw, and otoscopic examination showed tympanic membrane rupture associated with hyperplastic tissue at the entrance of the middle ear. Standard MRI sequences allowed for the identification of a severely expanded bulla containing material that was isointense to brain tissue on T1-weighted images and of mixed intensity on T2-weighted and fluid-attenuated inversion recovery sequences.