Manipulation of mass transport rates using bead-in-a-tube method.

In ultralow Pu analyses, the gold standard is thermal ionization mass spectrometry (TIMS), which requires pure sources to achieve its performance. This purity is achieved through step-wise purifications. In this work single, anion-exchange beads were trapped in the tubing to allow for dynamic solution cycling over the surface of the beads to improve the rates of metal complex uptake.

Tandem column isolation of zirconium-89 from cyclotron bombarded yttrium targets using an automated fluidic platform: Anion exchange to hydroxamate resin columns.

The development of a tandem column purification method for the preparation of high-purity Zr(IV) oxalate is presented. The primary column was a macroporous strongly basic anion exchange resin on styrene divinylbenzene co-polymer. The secondary column, with an internal volume of 33 μL, was packed with hydroxamate resin.

Optimized anion exchange column isolation of zirconium-89 (Zr) from yttrium cyclotron target: Method development and implementation on an automated fluidic platform.

Zirconium-89 (Zr), produced by the (p, n) reaction from naturally monoisotopic yttrium (Y), is a promising positron emitting isotope for immunoPET imaging. Its long half-life of 78.4 h is sufficient for evaluating slow physiological processes.

Hydroxamate column-based purification of zirconium-89 (Zr) using an automated fluidic platform.

Zirconium-89 (Zr) is a long-lived (t = 78.4h) positron-emitting isotope that is useful for positron emission tomography (PET) based diagnostic imaging using radiolabeled antibodies. Hydroxamate resin columns are predominantly used for the purification of Zr from cyclotron bombarded Y targets dissolved in strong HCl.