Publications by authors named "Nathaniel Bendahan"

Article Synopsis
  • Williams syndrome (WS) is a rare genetic disorder linked to chromosome 7, characterized by developmental delays and various neuropsychiatric issues, including movement disorders and psychiatric conditions.
  • The study presents two adult cases of WS with severe treatment-resistant schizoaffective disorder and associated movement issues, such as parkinsonism and dystonia, observed after clozapine treatment.
  • The findings suggest that low-dose levodopa may effectively alleviate movement symptoms without worsening psychotic or mood symptoms, indicating new potential treatment avenues for individuals with WS.
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Article Synopsis
  • Multiple system atrophy (MSA) is a neurodegenerative disease characterized by abnormal protein aggregation, resulting in symptoms like dysautonomia, parkinsonism, and ataxia.
  • This study aimed to assess the accuracy of diagnostic criteria for MSA, emphasizing the role of new MRI markers in diagnosis.
  • Results showed that while the criteria had high specificity (99-100%), their sensitivity was low initially but improved over time; excluding MRI features from the criteria significantly increased sensitivity without affecting specificity.
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Electroencephalography (EEG) is an effective and non-invasive technique commonly used to monitor brain activity and assist in outcome prediction for comatose patients post cardiac arrest. EEG data may demonstrate patterns associated with poor neurological outcome for patients with hypoxic injury. Thus, both quantitative EEG (qEEG) and clinical data contain prognostic information for patient outcome.

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The COVID-19 crisis has worsened the pre-existing barriers to accessing neurological specialist care in Low and middle income countries. Telemedicine has been available for well over 2 decades but has not been widely adopted in LMIC's due to issues around cost, feasibility, infrastructure and regulation. Virtual care is an offshoot of traditional telemedicine leveraging the widely available internet enabled devices to connect patients with their healthcare providers.

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Background: A common neurological complication of critical illness is delirium, defined as an acute change in level of consciousness, with impaired attention and disorganized thinking. Patients with delirium have increased risk of long-term cognitive dysfunction and mortality. The cause is unknown, which limits our ability to design therapeutic interventions.

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