Publications by authors named "Nathan Y Chang"
Article Synopsis
- Macrocyclization improves the effectiveness of peptides as therapeutics, addressing their limitations.
- A new amino acid, p-chloropropynyl phenylalanine (pCPF), enables spontaneous macrocyclization of peptides during in vitro translation when combined with cysteine.
- This method allows for various ring sizes and the testing of different non-canonical amino acids (ncAAs), paving the way for innovative macrocyclic peptide libraries and enhanced translation studies.
